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How to get fromMississippi to Indianaby plane, train, bus (Greyhound), train (Amtrak) or car

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There are 6 ways to get from Mississippi to Indiana by plane, train, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport, train

    best
    1. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane plane MEM - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    3h 43m
    $120–589
  2. Bus via St. Louis (Greyhound)

    cheapest
    1. Take the bus from Jackson to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    15h 30m
    $101–264
  3. Train (Amtrak)

    1. Take the train from Jackson to Chicago Union Stationtrain train City of New Orleans
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    21h 25m
    $154–229
  4. Drive 634.5 mi

    1. Drive from Jackson to Indianapoliscar car 634.5 mi
    11h 57m
    $116–168
  5. Fly to Chicago O'Hare International Airport, train

    1. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane plane MEM - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 11m
    $260–529
  6. Bus

    1. Take the bus from Jackson to Memphis Bus Stationbus bus Greyhound US1173
    2. Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus bus Memphis
    16h 22m
    $141–284

Mississippi to Indiana by bus (Greyhound)

Calendar7Weekly Buses
Duration15h 30mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

What companies run services between Mississippi, USA and Indiana, USA?

You can take a bus from Jackson to Indianapolis Union Station via St Louis Bus Station in around 15h 30m. Alternatively, you can take a train from Jackson to Indianapolis via Chicago Union Station in around 21h 25m.

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Need to know: Greyhound

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