There are 6 ways to get from Mississippi to Indiana by plane, train, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport, train
best- Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane MEM - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
3h 43m$120–589Bus via St. Louis (Greyhound)
cheapest- Take the bus from Jackson to St Louis Bus Stationbus Greyhound US1173
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
15h 30m$101–264Train (Amtrak)
- Take the train from Jackson to Chicago Union Stationtrain City of New Orleans
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
21h 25m$154–229Drive 634.5 mi
- Drive from Jackson to Indianapoliscar 634.5 mi
11h 57m$116–168Fly to Chicago O'Hare International Airport, train
- Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane MEM - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
4h 11m$260–529Bus
- Take the bus from Jackson to Memphis Bus Stationbus Greyhound US1173
- Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus Memphis
16h 22m$141–284
Mississippi to Indiana by bus (Greyhound)
Questions & Answers
The cheapest way to get from Mississippi to Indiana is to bus via St. Louis which costs $100 - $270 and takes 15h 30m.
The fastest way to get from Mississippi to Indiana is to fly and train which takes 3h 43m and costs $120 - $600.
No, there is no direct bus from Mississippi to Indiana station. However, there are services departing from Jackson and arriving at Indianapolis Union Station via St Louis Bus Station. The journey, including transfers, takes approximately 15h 30m.
No, there is no direct train from Mississippi to Indiana. However, there are services departing from Jackson and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 21h 25m.
The distance between Mississippi and Indiana is 532 miles. The road distance is 638.2 miles.
The best way to get from Mississippi to Indiana without a car is to bus via St. Louis which takes 15h 30m and costs $100 - $270.
It takes approximately 3h 43m to get from Mississippi to Indiana, including transfers.
Mississippi to Indiana bus services, operated by Greyhound USA, depart from Jackson station.
Mississippi to Indiana train services, operated by Amtrak, depart from Jackson station.
The best way to get from Mississippi to Indiana is to bus via St. Louis which takes 15h 30m and costs $100 - $270. Alternatively, you can train, which costs $150 - $230 and takes 21h 25m.
What companies run services between Mississippi, USA and Indiana, USA?
You can take a bus from Jackson to Indianapolis Union Station via St Louis Bus Station in around 15h 30m. Alternatively, you can take a train from Jackson to Indianapolis via Chicago Union Station in around 21h 25m.
- Website
- aa.com
Flights from Memphis to Chicago O'Hare International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $60–360
- Website
- united.com
Flights from Memphis to Chicago O'Hare International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $60–360
- Website
- southwest.com
Flights from Memphis to Chicago Midway International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $90–550
- Website
- delta.com
Flights from Memphis to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–440
Flights from Memphis to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 24m
- When
- Tuesday and Wednesday
- Estimated price
- $80–430
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jackson to Chicago Union Station
- Ave. Duration
- 15h 31m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–45
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $70–210
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from Jackson to Memphis Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - West Memphis to Indianapolis
- Ave. Duration
- 9h 31m
- Frequency
- 3 times a week
- Estimated price
- $90–210
- Schedules at
- tornadobus.com
- Adults 11-59
- $90–210
Want to know more about travelling around United States
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More Questions & Answers
Mississippi to Indiana bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Indiana is 1h ahead of Mississippi. It is currently 3:43 AM in Mississippi and 4:43 AM in Indiana.
Mississippi to Indiana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Mississippi to Indiana is 638 miles. It takes approximately 11h 57m to drive from Mississippi to Indiana.
Book your Mississippi to Indiana train tickets online with Omio.
Book your Mississippi to Indiana bus tickets online with Omio and FlixBus.
There are 578+ hotels available in Indiana.







