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How to get fromDes Moines to Ohioby plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

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There are 10 ways to get from Des Moines to Ohio by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 23m
    $181–974

  2. Bus #2

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago to Columbus - Mound Stbus bus Chicago
    15h 55m
    $85–185

  3. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis to Columbusbus bus FlixBus N2640 / ...
    14h 19m
    $99–186

  4. Drive 619.5 mi

    1. Drive from Des Moines to Columbuscar car 619.5 mi
    11h 27m
    $114–164

  5. Fly to John Glenn Columbus International Airport

    1. Fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH)plane plane DSM - CMH
    5h 2m
    $160–874

  6. Fly to Covington

    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    5h 32m
    $171–976

  7. Fly to Dayton

    1. Fly from Des Moines (DSM) to Dayton (DAY)plane plane DSM - DAY
    5h 47m
    $105–573

  8. Fly to Akron

    1. Fly from Des Moines (DSM) to Akron (CAK)plane plane DSM - CAK
    5h 38m
    $93–451

  9. Fly to Detroit, bus

    1. Fly from Des Moines (DSM) to Detroit (DTW)plane plane DSM - DTW
    2. Take the bus from Dearborn to Toledobus bus
    5h 21m
    $149–667

  10. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Columbusbus bus Greyhound US0421
    15h 20m
    $106–206

Des Moines to Ohio by bus and foot

Calendar7Weekly Services
Duration14h 19mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Ohio, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Columbus via Indianapolis, Illinois St (Greyhound Bus Station) and Indianapolis in around 14h 19m.

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