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How to get fromDes Moines to Ohioby plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound) or train

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There are 10 ways to get from Des Moines to Ohio by plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 18m
    $171–924

  2. Bus via Columbus - Mound St

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago to Columbus - Mound Stbus bus Chicago
    15h 55m
    $74–176

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus N2640 / ...
    15h 30m
    $89–191

  4. Drive 619.5 mi

    1. Drive from Des Moines to Columbuscar car 619.5 mi
    11h 26m
    $114–164

  5. Fly to John Glenn Columbus International Airport

    1. Fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH)plane plane DSM - CMH
    4h 39m
    $150–824

  6. Fly to Dayton

    1. Fly from Des Moines (DSM) to Dayton (DAY)plane plane DSM - DAY
    5h 44m
    $280–1,623

  7. Fly to Covington

    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    5h 54m
    $211–1,126

  8. Fly to Akron

    1. Fly from Des Moines (DSM) to Akron (CAK)plane plane DSM - CAK
    6h 9m
    $138–721

  9. Fly to Detroit, bus

    1. Fly from Des Moines (DSM) to Detroit (DTW)plane plane DSM - DTW
    2. Take the bus from Dearborn to Toledobus bus
    5h 26m

  10. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Toledotrain train
    3. Take the bus from Toledo to Columbus - Mound Stbus bus
    16h 3m
    $92–276

Des Moines to Ohio by bus

Calendar13Weekly Buses
Duration15h 30mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Ohio, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Des Moines to Columbus via Chicago Bus Station in around 15h 30m.

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