There are 10 ways to get from South Carolina to Indiana by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Charlotte to Evansville  •  2 h 25 min

  1. Fly from Charlotte (CLT) to Evansville (EVV) CLT - EVV

$271 - $1,021

Cheapest option

Bus  •  20 h 25 min

  1. Take the bus from Florence to Atlanta, GA 0983 / ...
  2. Take the bus from Marta Civic Center Station - Nb to Indianapolis, IN

$97 - $129

8 alternative options

Fly Charlotte to Fort Wayne  •  2 h 31 min

  1. Fly from Charlotte (CLT) to Fort Wayne (FWA) CLT - FWA

$403 - $1,338

Fly Charlotte to Indianapolis  •  3 h 9 min

  1. Fly from Charlotte (CLT) to Indianapolis (IND) CLT - IND

$230 - $395

Fly Charlotte to South Bend  •  3 h 5 min

  1. Fly from Charlotte (CLT) to South Bend (SBN) CLT - SBN

$318 - $1,308

Fly Charlotte to Chicago Midway, train  •  4 h 13 min

  1. Fly from Charlotte (CLT) to Chicago Midway (MDW) CLT - MDW
  2. Take the train from Van Buren St. to East Chicago

$281 - $589

Line 11 bus to Charleston, fly to Chicago Midway, train  •  6 h 1 min

  1. Take the line 11 bus from N. Charleston SuperStop on Rivers Ave to Centre Pointe Dr / Tanger Outlet Blvd
  2. Fly from Charleston (CHS) to Chicago Midway (MDW) CHS - MDW
  3. Take the train from Van Buren St. to East Chicago

$217 - $662

Bus via Nashville, Tn  •  19 h 7 min

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Nashville, Tn
  4. Take the bus from Nashville, Tn to Louisville, Ky
  5. Take the bus from Louisville, KY to Indianapolis, IN

$115 - $271

Train, Amtrak Thruway  •  24 h 18 min

  1. Take the train from Florence Amtrak to Richmond Staples Mill Amtrak
  2. Take the Amtrak Thruway from Richmond - Staples, VA to Charlottesville, VA
  3. Take the train from Charlottesville Amtrak to Indianapolis Amtrak

Drive  •  11 h 45 min

  1. Drive from Florence to Indianapolis 700.4 miles

$65 - $100

Questions & Answers

The cheapest way to get from South Carolina to Indiana is to drive which costs $65 - $100 and takes 11 h 45 min.

More details

The quickest way to get from South Carolina to Indiana is to fly which costs $270 - $1,100 and takes 2 h 25 min.

More details

The distance between South Carolina and Indiana is 560 miles. The road distance is 700.4 miles.

Get driving directions

It takes approximately 2 h 25 min to get from South Carolina to Indiana, including transfers.

More details

No, there is no direct bus from South Carolina to Indiana. However, there are services departing from Florence, Sc and arriving at Indianapolis, IN via Savannah, Ga, Atlanta, Ga, Nashville, Tn and Louisville, KY. The journey, including transfers, takes approximately 19 h 7 min.

More details

What companies run services between South Carolina, USA and Indiana, USA?

American Airlines and Delta fly from Rock Hill to Evansville 4 times a day. Alternatively, you can take a bus from Florence to Indianapolis via Savannah, Ga, Atlanta, Ga, Nashville, Tn, Louisville, Ky, and Louisville, KY in around 19 h 7 min.

Airlines
Delta
Website
delta.com
Flights from Charlotte to Evansville via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$170 - $900
Flights from Charlotte to Fort Wayne via Detroit
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$420 - $2,300
Flights from Charlotte to Indianapolis via Detroit
Ave. Duration
3 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $650
Flights from Charlotte to Indianapolis via Atlanta
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$250 - $650
Flights from Charlotte to South Bend via Detroit
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$230 - $1,200
Flights from Charlotte to South Bend via Atlanta
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$240 - $1,200
Flights from Charlotte to Chicago Midway via Detroit
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$210 - $700
Flights from Charlotte to Chicago Midway via Atlanta
Ave. Duration
4 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $700
Flights from Charleston to Chicago Midway via Atlanta
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$280 - $1,400
Flights from Charleston to Chicago Midway via Detroit
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$280 - $1,400
Southwest Airlines
Website
southwest.com
Flights from Charlotte to Indianapolis via Chicago Midway
Ave. Duration
3 h 40 min
When
Sunday
Estimated price
$320 - $650
Flights from Charlotte to Chicago Midway
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Nashville
Ave. Duration
4 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Baltimore
Ave. Duration
4 h 30 min
When
Monday to Friday
Estimated price
$310 - $800
Flights from Charleston to Chicago Midway
Ave. Duration
2 h 7 min
When
Every day
Estimated price
$350 - $1,600
Flights from Charleston to Chicago Midway via Nashville
Ave. Duration
4 h 5 min
When
Monday to Saturday
Estimated price
$350 - $1,600
Flights from Charleston to Chicago Midway via Baltimore
Ave. Duration
4 h 27 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,600
American Airlines
Website
aa.com
Flights from Charlotte to Evansville
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$170 - $850
Flights from Charlotte to Fort Wayne
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$410 - $2,600
Flights from Charlotte to Indianapolis
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$280 - $700
Flights from Charlotte to South Bend
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$230 - $1,200
United Airlines
Website
united.com
Flights from Charlotte to Indianapolis via Washington Dulles
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$270 - $600
Flights from Charlotte to South Bend via Chicago O'Hare
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$260 - $1,300
Train operators
South Shore Line
Phone
+1 219-926-5744
Website
nictd.com
Train from Van Buren St. to East Chicago
Ave. Duration
43 min
Frequency
Every 15 minutes
Estimated price
$6 - $7
Schedules at
nictd.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Florence Amtrak to Richmond Staples Mill Amtrak
Ave. Duration
5 h 25 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $340
Train from Charlottesville Amtrak to Indianapolis Amtrak
Ave. Duration
15 h 23 min
Frequency
3 times a week
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$360 - $550
Bus operators
CARTA
Phone
+1 843-724-7420
Website
ridecarta.com
Bus from N. Charleston SuperStop on Rivers Ave to Centre Pointe Dr / Tanger Outlet Blvd
Ave. Duration
22 min
Frequency
Hourly
Estimated price
$2 - $3
Schedules at
ridecarta.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Nashville, Tn
Ave. Duration
3 h 30 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from Nashville, Tn to Louisville, Ky
Ave. Duration
4 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Louisville, KY to Indianapolis, IN
Ave. Duration
2 h 24 min
Frequency
Twice daily
Estimated price
$12 - $23
Schedules at
us.megabus.com
Bus from Marta Civic Center Station - Nb to Indianapolis, IN
Ave. Duration
10 h 46 min
Frequency
Twice daily
Estimated price
$50 - $65
Schedules at
us.megabus.com

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