There are 9 ways to get from South Carolina to Indiana by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Evansville  •  2 h 30 min

  1. Fly from Charlotte (CLT) to Evansville (EVV) CLT - EVV

$271 - $1,021

Cheapest option

Bus Megabus  •  18 h 1 min

  1. Take the bus from Florence, SC to Atlanta, Ga Fayetteville
  2. Take the bus from Marta Civic Center Station - Nb to Delaware St & Market St Indianapolis

$91 - $123

7 alternative options

Fly to Fort Wayne  •  2 h 19 min

  1. Fly from Charlotte (CLT) to Fort Wayne (FWA) CLT - FWA

$403 - $1,338

Fly to Indianapolis  •  3 h 10 min

  1. Fly from Charlotte (CLT) to Indianapolis (IND) CLT - IND

$230 - $395

Fly to South Bend  •  2 h 59 min

  1. Fly from Charlotte (CLT) to South Bend (SBN) CLT - SBN

$318 - $1,308

Fly to Chicago Midway, train  •  4 h 13 min

  1. Fly from Charlotte (CLT) to Chicago Midway (MDW) CLT - MDW
  2. Take the train from Van Buren St. to East Chicago

$281 - $589

Bus via Nashville, Tn  •  18 h 30 min

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Nashville, Tn
  4. Take the bus from Nashville, Tn to Louisville, Ky
  5. Take the bus from Louisville, KY to Indianapolis, IN - Amtrak

$131 - $288

Train, bus  •  24 h 18 min

  1. Take the train from Florence Amtrak to Richmond Staples Mill Amtrak
  2. Take the bus from Richmond Staples Mill Amtrak to Charlottesville Amtrak
  3. Take the train from Charlottesville Amtrak to Indianapolis Amtrak

Drive  •  11 h 45 min

  1. Drive from Florence to Indianapolis 700.4 miles

$65 - $100

Questions & Answers

No, there is no direct bus from South Carolina to Indiana. However, there are services departing from Florence, Sc and arriving at Indianapolis, IN - Amtrak via Savannah, Ga, Atlanta, Ga, Nashville, Tn and Louisville, KY. The journey, including transfers, takes approximately 18 h 30 min.

More details

The distance between South Carolina and Indiana is 560 miles. The road distance is 700.4 miles.

Get driving directions

The best way to get from South Carolina to Indiana without a car is to bus which takes 18 h 1 min and costs .

More details

It takes approximately 2 h 30 min to get from South Carolina to Indiana, including transfers.

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South Carolina to Indiana bus services, operated by Greyhound USA, depart from Florence, Sc station.

More details

The best way to get from South Carolina to Indiana is to fly which takes 2 h 30 min and costs . Alternatively, you can bus, which costs and takes 18 h 1 min.

Mode details

The quickest flight from Charlotte Airport to Evansville Airport is the direct flight which takes 1 h 42 min.

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South Carolina to Indiana bus services, operated by Amtrak, arrive at Indianapolis, IN - Amtrak station.

More details

Yes, the driving distance between South Carolina to Indiana is 700 miles. It takes approximately 11 h 45 min to drive from South Carolina to Indiana.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Charlotte Airport to Evansville Airport.

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Map of how to get from South Carolina to Indiana.
Launch map view
  • Distance: 560.4 miles
  • Duration: 2 h 30 min

What companies run services between South Carolina, USA and Indiana, USA?

American Airlines, Delta and United Airlines fly from Rock Hill to Evansville every 4 hours. Alternatively, you can take a bus from Florence to Indianapolis via Atlanta, Ga, Five Points Station, Civic Center Station, and Marta Civic Center Station - Nb in around 18 h 1 min.

Airlines
American Airlines
Website
aa.com
Flights from Charlotte to Evansville
Ave. Duration
1 h 46 min
When
Every day
Estimated price
$170 - $850
Flights from Charlotte to Evansville via Chicago O'Hare
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$200 - $950
Flights from Charlotte to Fort Wayne
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$410 - $2,600
Flights from Charlotte to Indianapolis
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$280 - $700
Flights from Charlotte to South Bend
Ave. Duration
1 h 49 min
When
Every day
Estimated price
$230 - $1,200
Delta
Website
delta.com
Flights from Charlotte to Evansville via Atlanta
Ave. Duration
4 h 1 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $900
Flights from Charlotte to Evansville via Detroit
Ave. Duration
4 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $950
Flights from Charlotte to Fort Wayne via Detroit
Ave. Duration
3 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$420 - $2,300
Flights from Charlotte to Indianapolis via Atlanta
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$250 - $650
Flights from Charlotte to South Bend via Detroit
Ave. Duration
4 h
When
Every day
Estimated price
$230 - $1,200
Flights from Charlotte to South Bend via Atlanta
Ave. Duration
4 h 22 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
Flights from Charlotte to Chicago Midway via Detroit
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$210 - $700
Flights from Charlotte to Chicago Midway via Atlanta
Ave. Duration
4 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $700
Southwest Airlines
Website
southwest.com
Flights from Charlotte to Indianapolis via Chicago Midway
Ave. Duration
3 h 40 min
When
Monday to Friday
Estimated price
$320 - $650
Flights from Charlotte to Chicago Midway
Ave. Duration
1 h 52 min
When
Every day
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Nashville
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Baltimore
Ave. Duration
4 h 35 min
When
Saturday
Estimated price
$310 - $800
United Airlines
Website
united.com
Flights from Charlotte to Evansville via Chicago O'Hare
Ave. Duration
4 h 18 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Charlotte to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 57 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $600
Flights from Charlotte to Indianapolis via Washington Dulles
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$270 - $600
Train operators
South Shore Line
Phone
+1 219-926-5744
Website
nictd.com
Train from Van Buren St. to East Chicago
Ave. Duration
43 min
Frequency
Every 15 minutes
Estimated price
$6 - $7
Schedules at
nictd.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Florence Amtrak to Richmond Staples Mill Amtrak
Ave. Duration
5 h 25 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $340
Train from Charlottesville Amtrak to Indianapolis Amtrak
Ave. Duration
15 h 23 min
Frequency
4 times a week
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$360 - $550
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Marta Civic Center Station - Nb to Delaware St & Market St Indianapolis
Ave. Duration
11 h 5 min
Frequency
Twice daily
Estimated price
$50 - $65
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Nashville, Tn
Ave. Duration
3 h 30 min
Frequency
Every 20 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from Nashville, Tn to Louisville, Ky
Ave. Duration
4 h
Frequency
Every 20 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Louisville, KY to Indianapolis, IN - Amtrak
Ave. Duration
2 h 10 min
Frequency
Twice daily
Website
amtrak.com
Bus from Richmond Staples Mill Amtrak to Charlottesville Amtrak
Ave. Duration
1 h 30 min
Frequency
3 times a day
Website
amtrak.com

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More Questions & Answers

There are 10+ hotels available in Indiana. Prices start at $100 USD per night.

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The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs .

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