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How to get fromDepew to Bostonby plane, train (Amtrak), bus (Flixbus, Greyhound) or car

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There are 4 ways to get from Depew to Boston by plane, train (Amtrak), bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    1h 33m
    $127–770
  2. Train (Amtrak)

    cheapest
    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    12h 33m
    $67–232
  3. Bus

    1. Take the bus from Buffalo to Syracuse Bus Stationbus bus FlixBus 2686 / ...
    2. Take the bus from Syracuse Bus Station to Bostonbus bus Greyhound US0270
    13h 13m
    $74–192
  4. Drive 443 mi

    1. Drive from Depew to Bostoncar car 443 mi
    7h 54m
    $81–117

Depew to Boston by bus and train (Amtrak)

Calendar7Weekly Services
Duration12h 33mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

What companies run services between Depew, NY, USA and Boston, MA, USA?

American Airlines, JetBlue Airways, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS) 4 times a day. Alternatively, Amtrak operates a train from Buffalo Depew Station to Boston once daily. Tickets cost $65–230 and the journey takes 11h 27m.

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