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How to get fromDepew to Brooklynby plane, subway, train (Amtrak), bus (Greyhound), car, bus, bus (Flixbus) or train

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There are 9 ways to get from Depew to Brooklyn by plane, subway, train (Amtrak), bus (Greyhound), car, bus, bus (Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Laguardia Airport, subway

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the subway from Jackson Hts-Roosevelt Av to 15 St-Prospect Parksubway subway
    2h 48m
    $90–503

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus Greyhound US0205 / ...
    10h 54m
    $55–105

  3. Train via Ny Moynihan Train Hall At Penn Station (Amtrak)

    1. Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    9h 58m
    $65–205

  4. Drive 352.6 mi

    1. Drive from Depew to Brooklyncar car 352.6 mi
    7h 17m
    $65–93

  5. Fly Buffalo Niagara International Airport to John F. Kennedy International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane plane BUF - JFK
    2h 10m
    $104–525

  6. Fly Buffalo Niagara International Airport to Newark Liberty International Airport, line 2 subway

    1. Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane plane BUF - EWR
    2. Take the subway from 34 St-Penn Station to Church Avsubway subway
    3h 18m
    $105–491

  7. Bus to Rochester, fly to John F. Kennedy International Airport

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to John F. Kennedy International Airport (JFK)plane plane ROC - JFK
    4h 6m
    $899–4,090

  8. Bus via Prospect Park (Flixbus)

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus 2686 / ...
    11h 4m
    $55–115

  9. Train

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    11h 33m
    $65–125

Depew to Brooklyn by bus, train, and subway (Amtrak)

Calendar28Weekly Services
Duration9h 58mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between Depew, NY, USA and Brooklyn, Kings County, NY, USA?

Amtrak operates a train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station 4 times a day. Tickets cost $60–200 and the journey takes 8h 10m. Alternatively, Greyhound USA operates a bus from Buffalo to Port Authority Bus Terminal 4 times a day. Tickets cost $50–100 and the journey takes 8h 5m. Trailways also services this route 3 times a day.

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Need to know: Greyhound

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