There are 5 ways to get from Depew to Chicago by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago O'Hare International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
2h 57m$94–495Train (Amtrak)
cheapest- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
11h 39m$57–162Bus
- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0170
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
14h 29m$57–122Drive 536 mi
- Drive from Depew to Chicagocar 536 mi
9h 6m$98–142Fly to Chicago Midway International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
2h 51m$139–775
Depew to Chicago by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Depew to Chicago is to bus which costs $55 - $130 and takes 14h 29m.
The fastest way to get from Depew to Chicago is to fly which takes 2h 51m and costs $130 - $800.
No, there is no direct bus from Depew to Chicago station. However, there are services departing from Broadway & Meridian Street and arriving at Chicago Bus Station via Buffalo and Cleveland Bus Station. The journey, including transfers, takes approximately 14h 29m.
The distance between Depew and Chicago is 497 miles. The road distance is 539.2 miles.
The best way to get from Depew to Chicago without a car is to train which takes 11h 39m and costs $55 - $170.
It takes approximately 2h 57m to get from Depew to Chicago, including transfers.
Depew to Chicago bus services, operated by Greyhound USA, depart from Buffalo station.
The best way to get from Depew to Chicago is to fly which takes 2h 57m and costs $90 - $500. Alternatively, you can train, which costs $55 - $170 and takes 11h 39m, you could also bus, which costs $55 - $130 and takes 14h 29m.
Depew to Chicago bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Chicago is 1h behind Depew. It is currently 4:42 PM in Depew and 3:42 PM in Chicago.
What companies run services between Depew, NY, USA and Chicago, IL, USA?
American Airlines, United Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $55–160 and the journey takes 10h 33m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $75–470
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 4h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $75–470
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Monday to Thursday
- Estimated price
- $170–950
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $75–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $50–65
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
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More Questions & Answers
Yes, the driving distance between Depew to Chicago is 539 miles. It takes approximately 9h 6m to drive from Depew to Chicago.
There are 1304+ hotels available in Chicago.