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How to get fromDepew to Pittsburghby bus (Greyhound), train (Amtrak), car, plane or bus

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There are 5 ways to get from Depew to Pittsburgh by bus (Greyhound), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Youngstown

    best
    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus Buffalo
    2. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    7h 9m
    $40–84

  2. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    8h 31m
    $47–157

  3. Drive 219.4 mi

    1. Drive from Depew to Pittsburghcar car 219.4 mi
    3h 50m
    $40–58

  4. Fly

    1. Fly from Buffalo Niagara International Airport (BUF) to Pittsburgh International Airport (PIT)plane plane BUF - PIT
    5h 21m
    $117–670

  5. Bus

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530
    9h 29m
    $42–182

Depew to Pittsburgh by bus

Calendar7Weekly Buses
Duration7h 9mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

What companies run services between Depew, NY, USA and Pittsburgh, PA, USA?

You can take a bus from Broadway & Meridian Street to Pittsburgh Intermodal Station via Buffalo, NY, Youngstown, OH, and Youngstown Bus Stop in around 7h 9m. Alternatively, you can take a bus from Broadway & Meridian Street to Pittsburgh Amtrak Station via Dick Road & AMTRAK Station, Buffalo Depew Station, and Cleveland Amtrak in around 8h 31m.

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