The average train between Wetzlar and Mainz takes 2h 56m and the fastest train takes 2h 38m. The train service runs several times per day from Wetzlar to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Wetzlar and Mainz. The earliest departure is at 6:44 AM in the morning, and the last departure from Wetzlar is at 8:32 PM which arrives into Mainz at 11:22 PM. All services require a transfer at Gießen Bahnhof and take an average of 2h 56m. The schedules shown below are for the next available departures.


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2h 50m • 2 changesWant to know about travelling from Wetzlar to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Mainz. However, there are services departing from Wetzlar station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 56m.
Wetzlar to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
Wetzlar to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mainz, Römisches Theater station.
Book your Wetzlar to Mainz train tickets online with Deutsche Bahn Regio (DB Regional) and Süwex.
The distance between Wetzlar and Mainz is 66.1 km. The road distance is 116 km.
You can take a train from Wetzlar Bahnhof to Mainz, Römisches Theater via Gießen Bahnhof and Frankfurt in around 2h 51m.