The average train between Wetzlar and Prague takes 11h 23m and the fastest train takes 9h 37m. The train service runs several times per day from Wetzlar to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Wetzlar and Prague. The earliest departure is at 6:44 AM in the morning, and the last departure from Wetzlar is at 8:32 PM which arrives into Prague at 12:21 PM. All services require a transfer at Gießen Bahnhof and take an average of 11h 23m. The schedules shown below are for the next available departures.




9h 37m • 4 changes




9h 49m • 4 changes




9h 49m • 4 changes




9h 50m • 4 changes




9h 37m • 4 changes




9h 49m • 4 changes




9h 49m • 4 changes




9h 50m • 4 changes




9h 37m • 4 changes




9h 49m • 4 changes




9h 49m • 4 changes




9h 50m • 4 changes




9h 49m • 4 changes




9h 49m • 4 changes




9h 50m • 4 changes
Arrives next day




19h 49m • 4 changes




9h 49m • 4 changes




9h 49m • 4 changes




9h 50m • 4 changes
Arrives next day




15h 49m • 4 changes
Want to know about travelling from Wetzlar to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Prague. However, there are services departing from Wetzlar station and arriving at Prague station via Frankfurt. The journey, including transfers, takes approximately 11h 23m.
Wetzlar to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
Wetzlar to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha Hlavni Nadrazi station.
Book your Wetzlar to Prague train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Die Länderbahn.
The distance between Wetzlar and Prague is 423.1 km. The road distance is 643 km.
You can take a train from Wetzlar Bahnhof to Praha Hlavni Nadrazi via Gießen Bahnhof, Frankfurt, Nürnberg Hbf, and Schwandorf in around 10h 26m.