The average train between Konstanz and Mainz takes 5h 50m and the fastest train takes 5h 8m. The train service runs several times per day from Konstanz to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Konstanz and Mainz. The earliest departure is at 6:39 AM in the morning, and the last departure from Konstanz is at 7:39 PM which arrives into Mainz at 3:47 AM. All services require a transfer, and take on average 5h 50m. The schedules shown below are for the next available departures.

5h 8m • 1 change

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6h 29m • 1 change

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Want to know about travelling from Konstanz to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Konstanz to Mainz. However, there are services departing from Konstanz station and arriving at Mainz station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 5h 50m.
Konstanz to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Konstanz Bahnhof station.
Konstanz to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mainz, Hauptbahnhof station.
Book your Konstanz to Mainz train tickets online with Deutsche Bahn Regio (DB Regional), Süwex and Deutsche Bahn Intercity (DB IC).
The distance between Konstanz and Mainz is 266.6 km. The road distance is 371 km.
You can take a train from Konstanz Bahnhof to Mainz, Hauptbahnhof via Karlsruhe Hauptbahnhof in around 5h 19m.