Train Slough to Holyhead from £128 | Tickets & Timetables

Trip Overview

The average train between Slough and Holyhead takes 4h 49m and the fastest train takes 4h 37m. The train service runs several times per day from Slough to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 49m
Duration: 284 mi
Distance: £128
Average price: 5 times a day
Frequency

Train

best

Take the train from London Euston to Holyheadtrain London Euston - Holyhead

5h 36m

£105–192

Slough to Holyhead train times

Trains run 5 times a day between Slough and Holyhead. The earliest departure is at 7:07 AM in the morning, and the last departure from Slough is at 7:08 PM which arrives into Holyhead at 11:51 PM. All services require a transfer at Tottenham Court Road Station and take an average of 4h 49m. The schedules shown below are for the next available departures.

Departing Monday, April 27, 2026

1:51 PM → 6:49 PM
4h 58m • 2 changes
4:09 PM → 8:55 PM
4h 46m • 2 changes
6:08 PM → 11:03 PM
4h 55m • 2 changes
7:08 PM → 11:51 PM
4h 43m • 2 changes

Departing Tuesday, April 28, 2026

7:07 AM → 11:48 AM
4h 41m • 2 changes
8:15 AM → 12:52 PM
4h 37m • 2 changes
1:51 PM → 6:49 PM
4h 58m • 2 changes
4:09 PM → 8:55 PM
4h 46m • 2 changes
Show more

Departing Wednesday, April 29, 2026

7:07 AM → 11:48 AM
4h 41m • 2 changes
8:15 AM → 12:52 PM
4h 37m • 2 changes
1:51 PM → 6:49 PM
4h 58m • 2 changes
4:09 PM → 8:55 PM
4h 46m • 2 changes
Show more

Departing Thursday, April 30, 2026

7:07 AM → 11:48 AM
4h 41m • 2 changes
8:15 AM → 12:52 PM
4h 37m • 2 changes
1:51 PM → 6:49 PM
4h 58m • 2 changes
4:09 PM → 8:55 PM
4h 46m • 2 changes
Show more

Departing Friday, May 1, 2026

7:07 AM → 11:48 AM
4h 41m • 2 changes
8:15 AM → 12:52 PM
4h 37m • 2 changes
1:51 PM → 6:49 PM
4h 58m • 2 changes
4:09 PM → 8:55 PM
4h 46m • 2 changes
Show more

Departing Saturday, May 2, 2026

7:51 AM → 12:52 PM
5h 1m • 2 changes
8:51 AM → 1:49 PM
4h 58m • 2 changes
11:51 AM → 4:51 PM
5h • 2 changes
2:51 PM → 7:48 PM
4h 57m • 2 changes
Show more

Departing Sunday, May 3, 2026

11:51 AM → 4:55 PM
5h 4m • 2 changes
4:51 PM → 9:49 PM
4h 58m • 2 changes
5:51 PM → 10:48 PM
4h 57m • 2 changes

Frequently asked questions

Want to know about travelling from Slough to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.