The average train between Durham and Holyhead takes 5h 30m and the fastest train takes 5h 2m. The train service runs several times per day from Durham to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Durham and Holyhead. The earliest departure is at 7:06 AM in the morning, and the last departure from Durham is at 9:18 PM which arrives into Holyhead at 2:31 AM. All services require a transfer, and take on average 5h 30m. The schedules shown below are for the next available departures.

5h 29m • 1 change

5h 25m • 1 change

5h 31m • 1 change
Arrives next day

5h 14m • 1 change

5h 29m • 1 change

5h 25m • 1 change

5h 31m • 1 change
Arrives next day

6h 32m • 1 change

5h 29m • 1 change

5h 25m • 1 change

5h 31m • 1 change
Arrives next day

5h 12m • 1 change
Want to know about travelling from Durham to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Durham to Holyhead. However, there are services departing from Durham station and arriving at Holyhead station via Newton-le-Willows. The journey, including transfers, takes approximately 5h 30m.
Durham to Holyhead train services, operated by TransPennine Express, depart from Durham station.
Durham to Holyhead train services, operated by TransPennine Express, arrive at Holyhead station.
Book your Durham to Holyhead train tickets online with TransPennine Express and Transport for Wales.
The distance between Durham and Holyhead is 257.7 km. The road distance is 413 km.
You can take a train from Durham to Holyhead via Newton-le-Willows in around 5h 49m.