The average train between Durham and Holyhead takes 5h 46m and the fastest train takes 5h 3m. There is a train service every few hours from Durham to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Durham and Holyhead. The earliest departure is at 4:37 AM at night, and the last departure from Durham is at 9:18 PM which arrives into Holyhead at 8:53 AM. All services require a transfer, and take on average 5h 46m. The schedules shown below are for the next available departures.

6h 8m • 1 change

5h 23m • 1 change

5h 33m • 1 change

5h 22m • 1 change

6h 8m • 1 change

5h 23m • 1 change

5h 33m • 1 change

5h 22m • 1 change

6h 2m • 1 change

5h 23m • 1 change

5h 33m • 1 change

5h 21m • 1 change

5h 45m • 1 change

5h 23m • 1 change

5h 33m • 1 change

5h 22m • 1 change
Want to know about travelling from Durham to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Durham to Holyhead. However, there are services departing from Durham station and arriving at Holyhead station via Newton-le-Willows. The journey, including transfers, takes approximately 5h 46m.
Durham to Holyhead train services, operated by TransPennine Express, depart from Durham station.
Durham to Holyhead train services, operated by TransPennine Express, arrive at Holyhead station.
Book your Durham to Holyhead train tickets online with TransPennine Express and Transport for Wales.
The distance between Durham and Holyhead is 257.7 km. The road distance is 413 km.
You can take a train from Durham to Holyhead via Newton-le-Willows in around 5h 50m.