The average train between Slough and Matlock takes 6h 28m and the fastest train takes 3h 39m. The train service runs several times per day from Slough to Matlock. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Slough and Matlock. The earliest departure is at 9:16 AM in the morning, and the last departure from Slough is at 11:19 PM which arrives into Matlock at 12:30 PM. All services require a transfer at Farringdon Without and take an average of 6h 28m. The schedules shown below are for the next available departures.



4h 14m • 3 changes



3h 39m • 3 changes



3h 40m • 3 changes



3h 40m • 3 changes
Want to know about travelling from Slough to Matlock? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Matlock. However, there are services departing from Slough station and arriving at Matlock station via Farringdon Without. The journey, including transfers, takes approximately 6h 28m.
Slough to Matlock train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to Matlock train services, operated by Elizabeth Line (TfL), arrive at Derby station.
Book your Slough to Matlock train tickets online with Elizabeth Line (TfL), Thameslink and East Midlands Railways.
The distance between Slough and Matlock is 192.4 km. The road distance is 270 km.
You can take a train from Slough to Matlock via Farringdon Without, Farringdon, London St Pancras Intl, and Derby in around 4h.