The average train between Pisa and Mainz takes 14h 44m and the fastest train takes 11h 34m. The train service runs several times per day from Pisa to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Mainz. The earliest departure is at 5:19 AM in the morning, and the last departure from Pisa is at 8:32 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Firenze S.M.N. and take an average of 14h 44m. The schedules shown below are for the next available departures.
Arrives next day




18h 46m • 4 changes
Arrives next day




18h 46m • 4 changes




13h 24m • 4 changes




12h 49m • 4 changes




13h 21m • 4 changes
Arrives next day




16h 6m • 4 changes




13h 24m • 4 changes




12h 49m • 4 changes




13h 21m • 4 changes
Arrives next day




16h 6m • 4 changes




13h 24m • 4 changes




12h 49m • 4 changes




13h 21m • 4 changes
Arrives next day




16h 6m • 4 changes
Want to know about travelling from Pisa to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa station and arriving at Mainz station via Firenze S.M.N.. The journey, including transfers, takes approximately 14h 44m.
Pisa to Mainz train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Mainz train services, operated by Trenitalia, arrive at Mainz, Hauptbahnhof station.
Book your Pisa to Mainz train tickets online with Trenitalia, Trenitalia Frecce and 4 other operators.
The distance between Pisa and Mainz is 716.2 km. The road distance is 1,068 km.
You can take a train from Pisa Centrale to Mainz, Hauptbahnhof via Firenze S.M.N., Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 12h 21m.