The average train between Pisa and Mainz takes 13h 14m and the fastest train takes 11h 34m. The train service runs several times per day from Pisa to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Mainz. The earliest departure is at 6:29 AM in the morning, and the last departure from Pisa is at 8:32 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Firenze S.M.N. and take an average of 13h 14m. The schedules shown below are for the next available departures.




12h 14m • 4 changes



11h 34m • 4 changes



12h 23m • 4 changesArrives next day




15h 6m • 4 changes



12h 14m • 4 changes



11h 40m • 4 changesArrives next day




18h 46m • 4 changes



12h 14m • 4 changes



11h 34m • 4 changes



12h 23m • 4 changesArrives next day




15h 6m • 4 changes



12h 14m • 4 changes



11h 34m • 4 changes



12h 23m • 4 changesArrives next day




15h 6m • 4 changesWant to know about travelling from Pisa to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa station and arriving at Mainz station via Firenze S.M.N.. The journey, including transfers, takes approximately 13h 14m.
Pisa to Mainz train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Mainz train services, operated by Trenitalia, arrive at Mainz, Hauptbahnhof station.
Book your Pisa to Mainz train tickets online with Trenitalia, Trenitalia Frecce and 4 other operators.
The distance between Pisa and Mainz is 716.2 km. The road distance is 1,068 km.
You can take a train from Pisa Centrale to Mainz, Hauptbahnhof via Firenze S.M.N., Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 12h 21m.