There are 8 ways to get from Pisa to Mainz by train, plane, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly
best- Take the train from Pisa Centrale to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)FLR - FRA
5h 54m€123–298Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Station443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationN77 / ...
21h 45m€63–156Train via Florence
- Take the train from Pisa Centrale to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
13h 29m€173–293Train, bus
- Take the train from Pisa Centrale to Genova P.Za PrincipeFb / ...
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Mannheim - Bus Station
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
17h 30m€77–179Drive 941.1 km
- Drive from Pisa to Mainz941.1 km
9h€145–209Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)BLQ - FRA
6h 28m€134–355Fly from Pisa International Airport
- Fly from Pisa International Airport (PSA) to Frankfurt (FRA)PSA - FRA
2h 14m€117–194Train
- Take the train from Pisa Centrale to Milano CentraleIc
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
15h 22m€149–284
Pisa to Mainz by train
Questions & Answers
The cheapest way to get from Pisa to Mainz is to bus which costs €60 - €160 and takes 21h 45m.
The fastest way to get from Pisa to Mainz is to fly which takes 2h 14m and costs €110 - €200.
No, there is no direct bus from Pisa to Mainz station. However, there are services departing from Pisa and arriving at Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station. The journey, including transfers, takes approximately 21h 45m.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa Centrale and arriving at Mainz, Römisches Theater via Florence Santa Maria Novella, Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 13h 29m.
The distance between Pisa and Mainz is 832 km. The road distance is 941.1 km.
The best way to get from Pisa to Mainz without a car is to train via Florence which takes 13h 29m and costs €170 - €300.
It takes approximately 5h 54m to get from Pisa to Mainz, including transfers.
Pisa to Mainz bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mainz train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Mainz is to train via Florence which takes 13h 29m and costs €170 - €300. Alternatively, you can fly, which costs €110 - €200 and takes 2h 14m, you could also bus, which costs €60 - €160 and takes 21h 45m.
What companies run services between Pisa, Italy and Mainz, Germany?
You can take a train from Pisa Centrale to Mainz, Römisches Theater via Florence Santa Maria Novella, Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 13h 29m. Alternatively, Air Dolomiti flies from Pisa International Airport (PSA) to Frankfurt (FRA) once a week.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €100–250
Flights from Florence Peretola Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–320
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €100–330
Flights from Pisa International Airport to Frankfurt
- Ave. Duration
- 1h 40m
- When
- Saturday
- Estimated price
- €100–350
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €100–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–320
Flights from Pisa International Airport to Frankfurt
- Ave. Duration
- 1h 40m
- When
- Saturday
- Estimated price
- €100–350
- Website
- swiss.com
Flights from Florence Peretola Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €85–340
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–280
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €14–24
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 28m
- Frequency
- Once daily
- Estimated price
- €15–85
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 1h 54m
- Frequency
- Every 4 hours
- Estimated price
- €17–40
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 3h 44m
- Frequency
- Once daily
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 19m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 5h 58m
- Frequency
- Every 4 hours
- Estimated price
- €19–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa - Via Fanti d'Italia Bus Stop to Mannheim - Bus Station
- Ave. Duration
- 13h
- Frequency
- 3 times a week
- Estimated price
- €50–75
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- €8–18
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Frankfurt central train station
- Ave. Duration
- 17h 30m
- Frequency
- Twice daily
- Estimated price
- €50–130
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Pisa to Mainz bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Mainz train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mainz is 941 km. It takes approximately 9h to drive from Pisa to Mainz.
Book your Pisa to Mainz bus tickets online with FlixBus.
There are 1146+ hotels available in Mainz.







































