There are 6 ways to get from Pisa to Mainz by plane, train (Trenitalia), bus, car, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Frankfurt (FRA)plane PSA - FRA
2h 17m€117–255Bus
cheapest- Take the bus from Pisa to Milano, Autostazione Lampugnanobus 1500 / ...
- Take the bus from Milan to Mainz central train stationbus FlixBus 476
18h 15m€72–127Train via Florence
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
13h 35m€174–309Drive 941.3 km
- Drive from Pisa to Mainzcar 941.3 km
9h 3m€148–214Train
- Take the train from Pisa Centrale to Milano Centraletrain Ic
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
15h 27m€171–307Train, night train
- Take the train from Pisa Centrale to La Spezia Centraletrain Ic
- Take the train from La Spezia Centrale to Como Camerlatatrain
- Take the train from Lugano to Zürich HBtrain Ic2 / ...
- Take the night train from Zuerich Hb to Karlsruhe Hbfnighttrain Nj
- Take the train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhoftrain 55 / ...
16h 24m€133–420
Pisa to Mainz by train
Questions & Answers
The cheapest way to get from Pisa to Mainz is to bus which costs €70 - €130 and takes 18h 15m.
The fastest way to get from Pisa to Mainz is to fly which takes 2h 17m and costs €110 - €260.
No, there is no direct bus from Pisa to Mainz station. However, there are services departing from Pisa and arriving at Mainz central train station via Milan. The journey, including transfers, takes approximately 18h 15m.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa Centrale and arriving at Mainz, Römisches Theater via Firenze S.M.N., Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 13h 35m.
The distance between Pisa and Mainz is 746 km. The road distance is 941.3 km.
The best way to get from Pisa to Mainz without a car is to train via Florence which takes 13h 35m and costs €170 - €310.
It takes approximately 2h 17m to get from Pisa to Mainz, including transfers.
Pisa to Mainz bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mainz train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Mainz is to fly which takes 2h 17m and costs €110 - €260. Alternatively, you can train via Florence, which costs €170 - €310 and takes 13h 35m, you could also bus, which costs €70 - €130 and takes 18h 15m.
What companies run services between Pisa, Italy and Mainz, Germany?
Air Dolomiti flies from Pisa International Airport (PSA) to Frankfurt (FRA) twice daily. Alternatively, you can take a train from Pisa Centrale to Mainz, Römisches Theater via Firenze S.M.N., Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 13h 35m.
- Website
- airdolomiti.it
Flights from Pisa International Airport to Frankfurt
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €100–490
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- €10–17
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- €45–80
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €9–16
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 3h 48m
- Frequency
- Once daily
- Estimated price
- €50–100
- Schedules at
- trenitalia.com
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- €10–21
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 6h
- Frequency
- Every 4 hours
- Estimated price
- €35–85
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 58 min
- Frequency
- Every 4 hours
- Estimated price
- €7–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 8m
- Frequency
- Twice a week
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–65
- 2nd Class
- €23–35
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €18–27
- Website
- https://int.bahn.de/en
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 25m
- Frequency
- Every 4 hours
- Estimated price
- €35–55
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- 5 times a day
- Estimated price
- €22–30
- Schedules at
- suewex.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from La Spezia Centrale to Como Camerlata
- Ave. Duration
- 4h 38m
- Frequency
- Twice a week
- Estimated price
- €17–22
- Website
- https://www.trenord.it/en/
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Lugano to Zürich HB
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- €60–180
- Website
- https://www.sbb.ch/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Zuerich Hb to Karlsruhe Hbf
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- €24–93
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €88–93
- Couchette Carriage
- €55–65
- Seating Carriage
- €24–29
.jpg "Nightjet train Innsbruck Hbf")
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Karlsruhe Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- €24–55
- Website
- https://int.bahn.de/en
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Milano, Autostazione Lampugnano
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €21–40
- Website
- https://www.flixbus.co.uk
Bus from Milan to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Pisa to Mainz bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Pisa to Mainz train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mainz is 941 km. It takes approximately 9h 3m to drive from Pisa to Mainz.
Book your Pisa to Mainz bus tickets online with Omio and FlixBus.
There are 406+ hotels available in Mainz.