There are 7 ways to get from Pisa to Mainz by train, plane, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly
best- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane FLR - FRA
5h 55m€118–308Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationbus N77 / ...
21h 10m€58–159Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
13h 32m€168–293Train, bus
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Frankfurt - Airport Bus Stationbus BlaBlaCar Bus
18h 6m€77–176Drive 941.3 km
- Drive from Pisa to Mainzcar 941.3 km
9h 3m€146–211Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Florence Santa Maria Novella to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane BLQ - FRA
6h 41m€136–340Train via Bellinzona
- Take the train from Pisa Centrale to Bellinzonatrain Ec
- Take the train from Bellinzona to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
15h 14m€199–315
Pisa to Mainz by train
Questions & Answers
The cheapest way to get from Pisa to Mainz is to bus which costs €55 - €160 and takes 21h 10m.
The fastest way to get from Pisa to Mainz is to train and fly which takes 5h 55m and costs €110 - €310.
No, there is no direct bus from Pisa to Mainz station. However, there are services departing from Pisa and arriving at Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station. The journey, including transfers, takes approximately 21h 10m.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa Centrale and arriving at Mainz, Römisches Theater via Florence Santa Maria Novella, Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 13h 32m.
The distance between Pisa and Mainz is 832 km. The road distance is 941.3 km.
The best way to get from Pisa to Mainz without a car is to train which takes 13h 32m and costs €160 - €300.
It takes approximately 5h 55m to get from Pisa to Mainz, including transfers.
Pisa to Mainz bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mainz train services, operated by Trenitalia EuroCity, depart from Pisa Centrale station.
The best way to get from Pisa to Mainz is to train which takes 13h 32m and costs €160 - €300. Alternatively, you can bus, which costs €55 - €160 and takes 21h 10m.
What companies run services between Pisa, Italy and Mainz, Germany?
You can take a train from Pisa Centrale to Mainz, Römisches Theater via Florence Santa Maria Novella, Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 13h 32m. Alternatively, you can take a bus from Pisa to Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station in around 21h 10m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–250
Flights from Florence Peretola Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €110–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–310
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €100–320
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €95–310
- Website
- swiss.com
Flights from Florence Peretola Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €85–330
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–280
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 23m
- Frequency
- Twice a week
- Estimated price
- €40–85
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €60–85
- 2nd Class
- €40–55
Train from Pisa Centrale to Bellinzona
- Ave. Duration
- 7h 24m
- Frequency
- Twice a week
- Estimated price
- €85–140
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €95–140
- 2nd Class
- €85–120
Train from Bellinzona to Mannheim Hbf
- Ave. Duration
- 5h 11m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €110–160
- 2nd Class
- €100–140
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 2h 2m
- Frequency
- Every 4 hours
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 3h 21m
- Frequency
- Every 4 hours
- Estimated price
- €13–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa - Via Fanti d'Italia Bus Stop to Frankfurt - Airport Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- 3 times a week
- Estimated price
- €55–80
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- €8–11
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Frankfurt central train station
- Ave. Duration
- 17h 30m
- Frequency
- Twice daily
- Estimated price
- €45–140
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
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More Questions & Answers
Pisa to Mainz bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Mainz train services, operated by Trenitalia EuroCity, arrive at Bellinzona station.
Yes, the driving distance between Pisa to Mainz is 941 km. It takes approximately 9h 3m to drive from Pisa to Mainz.
Book your Pisa to Mainz train tickets online with Omio.
Book your Pisa to Mainz bus tickets online with Omio and FlixBus.
There are 1120+ hotels available in Mainz.







































