The average train between Mayen and Mainz takes 2h 30m and the fastest train takes 2h 5m. There is a train service every few hours from Mayen to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mayen and Mainz. The earliest departure is at 6:16 AM in the morning, and the last departure from Mayen is at 10:16 PM which arrives into Mainz at 1:40 AM. All services require a transfer, and take on average 2h 30m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mayen to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mayen to Mainz. However, there are services departing from Mayen station and arriving at Mainz station via Koblenz Hauptbahnhof. The journey, including transfers, takes approximately 2h 30m.
Mayen to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mayen Ostbahnhof station.
Mayen to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mainz, Hauptbahnhof station.
The distance between Mayen and Mainz is 84.4 km. The road distance is 132 km.
You can take a train from Mayen Ostbahnhof to Mainz, Hauptbahnhof via Koblenz Hauptbahnhof in around 2h 2m.