The average train between Mendrisio and Pisa takes 5h 43m and the fastest train takes 5h 7m. There is a train service every few hours from Mendrisio to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mendrisio and Pisa. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Pisa at 8:34 AM. All services require a transfer at Milano Centrale and take an average of 5h 43m. The schedules shown below are for the next available departures.


5h 10m • 2 changes


5h 7m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 7m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 7m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes


5h 8m • 2 changes


5h 10m • 2 changes


5h 10m • 2 changes
Want to know about travelling from Mendrisio to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mendrisio to Pisa. However, there are services departing from Mendrisio station and arriving at Pisa station via Milano Centrale. The journey, including transfers, takes approximately 5h 43m.
Mendrisio to Pisa train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Mendrisio station.
Mendrisio to Pisa train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Pisa Centrale station.
The distance between Mendrisio and Pisa is 265.1 km. The road distance is 441 km.
You can take a train from Mendrisio to Pisa Centrale via Milano Centrale and Firenze S.M.N. in around 5h 8m.