Train Mendrisio to Naples from €145 | Tickets & Timetables

Trip Overview

The average train between Mendrisio and Naples takes 6h 51m and the fastest train takes 5h 45m. The train service runs several times per day from Mendrisio to Naples. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 51m
Duration: 833 km
Distance: €145
Average price: Every 2 hours
Frequency

Train

best

Take the train from Mendrisio to Milano Centraletrain Re80
Take the train from Milano Centrale to Napoli Centraletrain Fr

5h 56m

€101–280

Mendrisio to Naples train times

Trains run every 2 hours between Mendrisio and Naples. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Naples at 10:28 AM. All services require a transfer, and take on average 6h 51m. The schedules shown below are for the next available departures.

Departing Monday, May 11, 2026

12:18 PM → 6:03 PM
5h 45m • 1 change
2:18 PM → 8:05 PM
5h 47m • 1 change
3:18 PM → 10:32 PM
7h 14m • 1 change
4:18 PM → 11:22 PM
7h 4m • 1 change
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Departing Tuesday, May 12, 2026

6:18 AM → 12:03 PM
5h 45m • 1 change
7:18 AM → 1:10 PM
5h 52m • 1 change
8:18 AM → 2:33 PM
6h 15m • 1 change
10:18 AM → 4:03 PM
5h 45m • 1 change
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Departing Wednesday, May 13, 2026

6:18 AM → 12:03 PM
5h 45m • 1 change
7:18 AM → 1:10 PM
5h 52m • 1 change
8:18 AM → 2:33 PM
6h 15m • 1 change
10:18 AM → 4:03 PM
5h 45m • 1 change
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Departing Thursday, May 14, 2026

6:18 AM → 12:03 PM
5h 45m • 1 change
7:18 AM → 1:10 PM
5h 52m • 1 change
8:18 AM → 2:33 PM
6h 15m • 1 change
10:18 AM → 4:03 PM
5h 45m • 1 change
Show more

Departing Friday, May 15, 2026

6:18 AM → 12:03 PM
5h 45m • 1 change
7:18 AM → 1:10 PM
5h 52m • 1 change
8:18 AM → 2:33 PM
6h 15m • 1 change
10:18 AM → 4:03 PM
5h 45m • 1 change
Show more

Departing Saturday, May 16, 2026

6:18 AM → 12:03 PM
5h 45m • 1 change

Frequently asked questions

Want to know about travelling from Mendrisio to Naples? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.