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Mendrisio to Spoleto trains

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Trip Overview

The average train between Mendrisio and Spoleto takes 8h 14m and the fastest train takes 6h 30m. There is a train service every few hours from Mendrisio to Spoleto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 14m
Duration
763 km
Distance
€118
Average price
Every 2 hours
Frequency

Train

best
  1. Take the train from Mendrisio to Milano Centraletrain train
  2. Take the train from Milano Centrale to Roma Terminitrain train
  3. Take the train from Roma Termini to Spoletotrain train
6h 23m
€96–165

Mendrisio to Spoleto train times

Trains run every 2 hours between Mendrisio and Spoleto. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Spoleto at 11:00 AM. All services require a transfer at Milano Centrale and take an average of 8h 14m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

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    Arrives next day

    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia13h 44m • 2 changes

Departing Wednesday, October 14, 2026

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 33m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity7h 28m • 2 changes
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Departing Thursday, October 15, 2026

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 33m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity7h 28m • 2 changes
  • Show more

Departing Friday, October 16, 2026

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 33m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity7h 28m • 2 changes
  • Show more

Departing Saturday, October 17, 2026

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 33m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia Intercity7h 28m • 2 changes
  • Show more

Departing Sunday, October 18, 2026

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia6h 45m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

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    Swiss Federal Railways (SBB CFF FFS)ItaloTrenoTrenitalia7h 37m • 2 changes

Frequently asked questions

Want to know about travelling from Mendrisio to Spoleto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mendrisio to Spoleto.ExpandLaunch map view
  • Distance: 762.8 km
  • Duration: 8h 14m

What companies run services between Mendrisio, Switzerland and Spoleto, Italy?

You can take a train from Mendrisio to Spoleto via Milano Centrale and Roma Termini in around 6h 23m.

Operators