The train between Mendrisio and Venice takes 3h 45m. The train service runs several times per day from Mendrisio to Venice. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mendrisio and Venice. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 6:18 PM which arrives into Venice at 10:03 PM. All services require a transfer, and take on average 3h 45m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mendrisio to Venice? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mendrisio to Venice. However, there are services departing from Mendrisio station and arriving at Venice station via Milano Centrale. The journey, including transfers, takes approximately 3h 45m.
Mendrisio to Venice train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Mendrisio station.
Mendrisio to Venice train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Venezia Santa Lucia station.
The distance between Mendrisio and Venice is 264.4 km. The road distance is 324 km.
You can take a train from Mendrisio to Venezia Santa Lucia via Milano Centrale in around 4h 18m.