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Mannheim to Lyon trains

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Trip Overview

The average train between Mannheim and Lyon takes 10h 8m and the fastest train takes 5h 16m. The train service runs several times per day from Mannheim to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 8m
Duration
646 km
Distance
€150
Average price
Twice daily
Frequency

Mannheim to Lyon train times

Trains run twice daily between Mannheim and Lyon. The earliest departure is at 11:37 AM in the morning, and the last departure from Mannheim is at 7:00 PM which arrives into Lyon at 10:59 AM. All services require a transfer at Karlsruhe Hauptbahnhof and take an average of 10h 8m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui5h 20m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 22m • 2 changes
  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui5h 16m • 2 changes
  •  → 

    Arrives next day

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui15h 59m • 2 changes

Departing Saturday, November 21, 2026

  •  → 

    Deutsche Bahn Intercity (DB IC)Deutsche Bahn Intercity (DB IC)TGV inOui6h 24m • 2 changes

Frequently asked questions

Want to know about travelling from Mannheim to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mannheim to Lyon.ExpandLaunch map view
  • Distance: 646.3 km
  • Duration: 10h 8m

What companies run services between Mannheim, Germany and Lyon, France?

You can take a train from Mannheim, Hauptbahnhof to Lyon Part Dieu via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 7h 17m.

Operators