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Duration 16h 50m
Distance 618.8 km
Average price 59€
Frequency Weekly

Trip overview

The bus between Mannheim and Lyon takes 16h 50m. The bus runs, on average, once a week from Mannheim to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.


  1. Mannheim, Mannheim ZOB
  2. Karlsruhe, Hbf. - Süd, am Hintereingang
  3. Lyon
11h 30m
49€ - 68€

Mannheim to Lyon bus times

Buses run once a week between Mannheim and Lyon. The service departs Mannheim at 23:25 at night, which arrives into Lyon at 16:15. All services require a transfer at Karlsruhe and take an average of 16h 50m. The schedules shown below are for the next available departures.
Train services typically run at the following times each day These schedules are estimated
These schedules are estimated: The schedules shown above are estimated schedules based on typical services on the average day and may vary depending on when you plan to travel. Please make sure you confirm the departure/arrival times and availability with the operator before planning your trip.

Frequently asked questions

Want to know about travelling from Mannheim to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport?, What is the quickest option?, How much do tickets usually cost? and many more.

There is widespread community transmission globally.
Some travel restrictions are being lifted in France. For the latest travel status, please check the official page for France.

Learn More.

No, there is no direct bus from Mannheim to Lyon. However, there are services departing from Mannheim, Mannheim ZOB and arriving at Lyon, de Perrache - Galerie A via Karlsruhe, Hbf. - Süd, am Hintereingang. The journey, including transfers, takes approximately 11h 30m.

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It is 496 km from Mannheim to Lyon. It is approximately 618.8 km to drive.

Get driving directions

Mannheim to Lyon bus services, operated by FlixBus, depart from Mannheim, Mannheim ZOB station.

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Mannheim to Lyon bus services, operated by RegioJet, arrive at Lyon, de Perrache - Galerie A station.

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There are 2377+ hotels available in Lyon. Prices start at 75€ per night.

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