The average train between Mannheim and Milan takes 7h 46m and the fastest train takes 6h 40m. The train service runs several times per day from Mannheim to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mannheim and Milan. The earliest departure is at 3:31 AM at night, and the last departure from Mannheim is at 11:00 PM which arrives into Milan at 9:17 AM. All services require a transfer at Basel SBB and take an average of 7h 46m. The schedules shown below are for the next available departures.


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Want to know about travelling from Mannheim to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Milan. However, there are services departing from Mannheim station and arriving at Milan station via Basel SBB. The journey, including transfers, takes approximately 7h 46m.
Mannheim to Milan train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Milan train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Milano Centrale station.
Book your Mannheim to Milan train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Mannheim and Milan is 450.8 km. The road distance is 582 km.
You can take a train from Mannheim, Hauptbahnhof to Milano Centrale via Basel SBB and Lugano in around 8h 14m.