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How to get fromMannheim to Lyonby train (TGV), bus, car, train, plane, or night train

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There are 7 ways to get from Mannheim to Lyon by train (TGV), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 12 / ...
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Lyon Perrachetrain train Tgv
    7h 10m
    €121–231

  2. Bus

    cheapest
    1. Take the bus from Mannheim - Bus Station to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    9h 5m
    €45–85

  3. Drive  597.8 km

    1. Drive from Mannheim to Lyoncar car 597.8 km
    5h 59m
    €96–139

  4. Train to Frankfurt, fly

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 37m
    €134–353

  5. Train via Lyon Part Dieu

    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 12 / ...
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    7h 18m
    €106–231

  6. Night train, train, bus

    1. Take the nighttrain from Mannheim Hbf to Basel Sbbnighttrain night train Nj
    2. Take the train from Basel SBB to Lausannetrain train
    3. Take the bus from Lausanne Bus Station to Lyon Perrache Bus Stationbus bus
    10h 22m
    €105–228

  7. Train, train to Strasbourg International Airport, fly

    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    3. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    5h 24m
    €138–420

Mannheim to Lyon by train

Calendar1Weekly Trains
Duration7h 10mAverage Duration
Ticket€121Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mannheim to Lyon.ExpandLaunch map view
  • Distance: 651.5 km
  • Duration: 7h 10m

What companies run services between Mannheim, Germany and Lyon, France?

You can take a train from Mannheim, Hauptbahnhof to Lyon Perrache via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 7h 10m. Alternatively, BlaBlaCar Bus operates a bus from Mannheim - Bus Station to Lyon - Gerland Bus Station twice daily. Tickets cost €45–80 and the journey takes 9h 5m. FlixBus also services this route twice daily.

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