Train Mainz to Zurich from CHF 108 | Tickets & Timetables

Trip Overview

The average train between Mainz and Zurich takes 5h 23m and the fastest train takes 4h 42m. There is an hourly train service from Mainz to Zurich. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 23m
Duration: 409 km
Distance: CHF 108
Average price: Hourly
Frequency

Train via Basel

best

Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
Take the train from Basel SBB to Zürich HBtrain Tgv / ...

5h 29m

CHF 66–219

Mainz to Zurich train times

Trains run hourly between Mainz and Zurich. The earliest departure is at 1:42 AM at night, and the last departure from Mainz is at 9:21 PM which arrives into Zurich at 5:49 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 5h 23m. The schedules shown below are for the next available departures.

Departing Thursday, April 30, 2026

5:18 AM → 10:00 AM
4h 42m • 2 changes
5:56 AM → 11:24 AM
5h 28m • 2 changes
7:00 AM → 12:00 PM
5h • 2 changes
7:57 AM → 1:24 PM
5h 27m • 2 changes
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Departing Friday, May 1, 2026

1:42 AM → 7:26 AM
5h 44m • 2 changes
7:00 AM → 12:00 PM
5h • 2 changes
7:57 AM → 1:24 PM
5h 27m • 2 changes
8:57 AM → 2:00 PM
5h 3m • 2 changes
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Departing Saturday, May 2, 2026

1:42 AM → 7:49 AM
6h 7m • 2 changes
5:18 AM → 10:24 AM
5h 6m • 2 changes
7:00 AM → 12:02 PM
5h 2m • 2 changes
7:57 AM → 1:24 PM
5h 27m • 2 changes
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Frequently asked questions

Want to know about travelling from Mainz to Zurich? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.