There are 9 ways to get from Mainz to Zurich by plane, train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Zurich Airport
best- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
2h 46mCHF 98–229Night train
cheapest- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
6h 22mCHF 29–95Train via Basel
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Zürich HBtrain Ir36 / ...
5h 14mCHF 61–178Bus
- Take the bus from Mainz central train station to Zurich Bus Stationbus FlixBus 476
8hCHF 35–60Fly Frankfurt to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Zürich HBtrain
4h 5mCHF 142–399Train to Stuttgart Airport, fly to Zurich Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane STR - ZRH
4h 35mCHF 133–369Train
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
6h 22mCHF 45–85Train via Karlsruhe
- Take the train from Mainz, Römisches Theater to Karlsruhe Hauptbahnhoftrain S6
- Take the train from Karlsruhe Hbf to Zuerich Hbtrain Ec
7h 17mCHF 92–179Drive 369.7 km
- Drive from Mainz to Zurichcar 369.7 km
3h 59mCHF 71–102
Mainz to Zurich by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Zurich is to bus which costs SFr 35 - SFr 60 and takes 8h.
The fastest way to get from Mainz to Zurich is to fly which takes 2h 46m and costs SFr 95 - SFr 230.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Zurich Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 8h.
Yes, there is an overnight train departing from Mainz Hbf and arriving at Zuerich Hb. This train operates every day. The journey takes approximately 6h 22m.
The distance between Mainz and Zurich is 328 km. The road distance is 369.7 km.
The best way to get from Mainz to Zurich without a car is to train via Basel which takes 5h 14m and costs SFr 60 - SFr 180.
It takes approximately 2h 46m to get from Mainz to Zurich, including transfers.
Mainz to Zurich bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Zurich train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Zurich is to fly which takes 2h 46m and costs SFr 95 - SFr 230. Alternatively, you can train via Basel, which costs SFr 60 - SFr 180 and takes 5h 14m, you could also bus, which costs SFr 35 - SFr 60 and takes 8h.
What companies run services between Mainz, Germany and Zurich, Switzerland?
Lufthansa, Condor Flugdienst, and Air Dolomiti fly from Frankfurt (FRA) to Zurich Airport (ZRH) every 2 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Zürich HB via Frankfurt and Basel SBB in around 5h 14m.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 65–380
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–260
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 65–380
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–260
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- CHF 60–340
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 90–200
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 130–380
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 140–420
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- CHF 50–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- CHF 27–60
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- CHF 30–60
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 45–85
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 45–85
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- CHF 26–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- CHF 26–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 3 times a week
- Estimated price
- CHF 29–92
- Website
- Nightjet
- Sleeper Carriage
- CHF 89–92
- Couchette Carriage
- CHF 55–70
- Seating Carriage
- CHF 29–34
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Römisches Theater to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 21m
- Frequency
- Every 4 hours
- Estimated price
- CHF 25–120
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Karlsruhe Hbf to Zuerich Hb
- Ave. Duration
- 3h 56m
- Frequency
- Once a week
- Estimated price
- CHF 66
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Zurich Bus Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- CHF 35–60
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Zurich bus services, operated by FlixBus, arrive at Zurich Bus Station.
Mainz to Zurich train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mainz to Zurich is 370 km. It takes approximately 3h 59m to drive from Mainz to Zurich.
Book your Mainz to Zurich train tickets online with Omio.
Book your Mainz to Zurich bus tickets online with Omio and FlixBus.
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