Mainz to Lyon train times
Trains run 3 times a day between Mainz and Lyon. The earliest departure is at 1:42 AM at night, and the last departure from Mainz is at 4:22 PM which arrives into Lyon at 10:59 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 11h 34m. The schedules shown below are for the next available departures.
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7h 3m • 2 changes
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7h 6m • 2 changes
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7h 1m • 2 changes
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Arrives next day
18h 37m • 2 changes
Departing Thursday, April 30, 2026
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11h 17m • 2 changes
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8h 2m • 2 changes
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Arrives next day
19h 2m • 2 changes
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
