The average train between Mainz and Genoa takes 15h 45m and the fastest train takes 11h 40m. The train service runs several times per day from Mainz to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Mainz and Genoa. The earliest departure is at 5:40 AM in the morning, and the last departure from Mainz is at 11:08 PM which arrives into Genoa at 3:54 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 15h 45m. The schedules shown below are for the next available departures.




12h 14m • 4 changes




12h 11m • 4 changes




13h 44m • 4 changes
Arrives next day




18h 44m • 4 changes




12h 14m • 4 changes




12h 11m • 4 changes




11h 40m • 4 changes
Arrives next day




18h 44m • 4 changes




12h 14m • 4 changes




12h 11m • 4 changes




11h 40m • 4 changes
Arrives next day




18h 44m • 4 changes
Want to know about travelling from Mainz to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Genoa. However, there are services departing from Mainz station and arriving at Genoa station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 15h 45m.
Mainz to Genoa train services, operated by Süwex, depart from Mainz, Hauptbahnhof station.
Mainz to Genoa train services, operated by Süwex, arrive at Genova Brignole station.
Book your Mainz to Genoa train tickets online with Süwex, Nederlandse Spoorwegen (NS) and 5 other operators.
The distance between Mainz and Genoa is 622.4 km. The road distance is 794 km.
You can take a train from Mainz, Hauptbahnhof to Genova Brignole via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 11h 41m.