Rome2Rio

How to get fromMainz to Romeby plane, train, bus, night train, or car

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There are 9 ways to get from Mainz to Rome by plane, train, bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Fiumicino International Airport

    best
    1. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4h 56m
    €65–249

  2. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train
    13h 17m
    €163–620

  3. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus bus N77
    21h 7m
    €99–170

  4. Train, night train

    1. Take the train from Frankfurt to München Hbftrain train 41 / ...
    2. Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    19h 18m
    €100–327

  5. Train to Stuttgart Airport, fly to Fiumicino International Airport

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    6h 30m
    €106–291

  6. Fly Frankfurt to Naples Airport, train

    1. Fly from Frankfurt (FRA) to Naples Airport (NAP)plane plane FRA - NAP
    2. Take the train from Napoli to Roma Terminitrain train
    6h 14m
    €124–342

  7. Fly Frankfurt to Florence Peretola Airport, train

    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    6h 22m
    €155–419

  8. Train to Cologne Bonn Airport, fly to Fiumicino International Airport

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane plane CGN - FCO
    6h 47m
    €87–286

  9. Drive 1,231.3 km

    1. Drive from Mainz to Romecar car 1,231.3 km
    11h 28m
    €192–277

Mainz to Rome by train and bus

Calendar7Weekly Services
Duration21h 7mAverage Duration
Ticket€99Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Rome, Italy?

easyJet, Condor Flugdienst, and three other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) hourly. Alternatively, you can take a train from Mainz, Römisches Theater to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 13h 17m.

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