Rome2Rio

How to get fromMainz to Romeby plane, train (Trenitalia), bus, train, night train, car or car train

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There are 10 ways to get from Mainz to Rome by plane, train (Trenitalia), bus, train, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Fiumicino International Airport

    best
    1. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4h 56m
    €55–190

  2. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train Ec
    5. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    13h 19m
    €132–425

  3. Bus via Pescara

    1. Take the bus from Frankfurt to Pescarabus bus
    2. Take the bus from Pescara to Roma Termini Giolittibus bus
    20h 19m
    €111–139

  4. Train, night train

    1. Take the train from Frankfurt to München Hbftrain train 41 / ...
    2. Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    19h 13m
    €108–511

  5. Train to Stuttgart Airport, fly to Fiumicino International Airport

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    6h 39m
    €105–279

  6. Train to Cologne Bonn Airport, fly to Fiumicino International Airport

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane plane CGN - FCO
    6h 44m
    €98–322

  7. Fly Frankfurt to Florence Peretola Airport, train

    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Florence Santa Maria Novella to Roma Terminitrain train
    6h 20m
    €131–324

  8. Bus

    1. Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus bus N77
    21h 45m
    €56–128

  9. Drive 1,231.2 km

    1. Drive from Mainz to Romecar car 1,231.2 km
    11h 28m
    €189–272

  10. Drive, car train

    1. Drive from Mainz to Fuldacar car
    2. Take the car train from Fulda to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Romecar car
    13h 3m
    €230–998

Mainz to Rome by train

Calendar84Weekly Trains
Duration13h 19mAverage Duration
Ticket€132Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Rome, Italy?

easyJet, Condor Flugdienst, and three other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) hourly. Alternatively, you can take a train from Mainz, Römisches Theater to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 13h 19m.

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