There are 8 ways to get from Mainz to Rome by plane, train, bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Fiumicino International Airport
best- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
4h 55m€51–148Train
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
13h 3m€148–402Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Roma Prenestina A1bus
18h 52m€154–214Train, night train
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the nighttrain from Muenchen Hbf to Roma Tiburtinanighttrain Nj
19h 31m€119–294Train to Stuttgart Airport, fly to Fiumicino International Airport
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
6h 40m€99–229Fly Frankfurt to Florence Peretola Airport, train
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Roma Terminitrain
6h 12m€153–374Bus via Frankfurt am Main
- Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus N77
21h 43m€114–194Drive 1,231.5 km
- Drive from Mainz to Romecar 1,231.5 km
11h 28m€230–333
Mainz to Rome by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Rome is to fly which costs €50 - €150 and takes 4h 55m.
The fastest way to get from Mainz to Rome is to fly which takes 4h 55m and costs €50 - €150.
No, there is no direct bus from Mainz to Rome. However, there are services departing from Wiesbaden-Mainz-Kastel Bahnhof and arriving at Roma Prenestina A1 via Wiesbaden Gartenfeldstraße P+R. The journey, including transfers, takes approximately 18h 52m.
No, there is no direct train from Mainz to Rome. However, there are services departing from Mainz, Römisches Theater and arriving at Roma Termini via Frankfurt, Basel SBB, Lugano and Milano Centrale. The journey, including transfers, takes approximately 13h 3m.
The distance between Mainz and Rome is 1019 km. The road distance is 1231.5 km.
The best way to get from Mainz to Rome without a car is to train which takes 13h 3m and costs €140 - €410.
It takes approximately 4h 55m to get from Mainz to Rome, including transfers.
Mainz to Rome bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Mainz to Rome train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Rome is to fly which takes 4h 55m and costs €50 - €150. Alternatively, you can train, which costs €140 - €410 and takes 13h 3m, you could also bus, which costs €150 - €220 and takes 18h 52m.
What companies run services between Mainz, Germany and Rome, Italy?
easyJet, ITA Airways, and three other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) every 2 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Roma Termini via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 13h 3m.
- Website
- lufthansa.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- €75–120
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €80–300
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €170–550
- Website
- ita-airways.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €130–390
Flights from Frankfurt to Fiumicino International Airport via Venice
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €75–120
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- €70–150
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €170–550
- Website
- condor.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Friday
- Estimated price
- €70–160
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Website
- eurowings.com
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- €70–150
- Website
- swiss.com
Flights from Stuttgart Airport to Fiumicino International Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €70–280
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–340
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–120
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €50–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €60–140
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €29–60
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- €35–65
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 47m
- Frequency
- 5 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 14h 6m
- Frequency
- Once daily
- Estimated price
- €55–140
- Website
- Nightjet
- Sleeper Carriage
- €110–140
- Couchette Carriage
- €85–100
- Seating Carriage
- €55–65
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 30 minutes
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Roma Prenestina A1
- Ave. Duration
- 17h 32m
- Frequency
- Once a week
- Estimated price
- €150–210
- Website
- Onebus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt central train station to Roma, Autostazione Tiburtina
- Ave. Duration
- 20h 5m
- Frequency
- Once daily
- Estimated price
- €110–180
- Website
- Flixbus
Want to know more about travelling around Italy
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Booking & Getting There
Mainz to Rome bus services, operated by Onebus, arrive at Roma Prenestina A1 station.
Mainz to Rome train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mainz to Rome is 1232 km. It takes approximately 11h 28m to drive from Mainz to Rome.
Book your Mainz to Rome train tickets online with Omio.
Book your Mainz to Rome bus tickets online with Omio.
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