Rome2Rio

How to get fromMainz to Romeby plane, train, bus, night train, or car

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There are 7 ways to get from Mainz to Rome by plane, train, bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Fiumicino International Airport

    best
    1. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    4h 51m
    €58–159

  2. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Roma Terminitrain train
    12h 33m
    €154–742

  3. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus bus N77
    21h 7m
    €108–180

  4. Train, night train

    1. Take the train from Frankfurt to München Hbftrain train 41 / ...
    2. Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    19h 21m
    €105–432

  5. Train, train to Stuttgart Airport, fly to Fiumicino International Airport

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    3. Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane plane STR - FCO
    6h 21m
    €91–315

  6. Fly Frankfurt to Florence Peretola Airport, train

    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    6h 44m
    €154–379

  7. Drive 1,231.5 km

    1. Drive from Mainz to Romecar car 1,231.5 km
    11h 28m
    €196–283

Mainz to Rome by train

Calendar76Weekly Trains
Duration12h 33mAverage Duration
Ticket€154Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Rome.ExpandLaunch map view
  • Distance: 1,019 km
  • Duration: 4h 51m

What companies run services between Mainz, Germany and Rome, Italy?

ITA Airways, easyJet, and two other airlines fly from Frankfurt (FRA) to Fiumicino International Airport (FCO) hourly. Alternatively, you can take a train from Mainz, Hauptbahnhof to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 12h 33m.

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