The average train between Prague and Brussels takes 13h 36m and the fastest train takes 10h 51m. The train service runs several times per day from Prague to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Prague and Brussels. The earliest departure is at 6:35 AM in the morning, and the last departure from Prague is at 11:46 PM which arrives into Brussels at 3:26 PM. All services require a transfer at Plzen Hlavni Nadrazi and take an average of 13h 36m. The schedules shown below are for the next available departures.
Arrives next day




16h 51m • 4 changes
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17h 40m • 4 changes




12h 51m • 4 changes




11h 39m • 4 changes
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16h 51m • 4 changes
Arrives next day




17h 40m • 4 changes




12h 51m • 4 changes




11h 39m • 4 changes
Arrives next day




16h 51m • 4 changes
Arrives next day




17h 40m • 4 changes




12h 51m • 4 changes




11h 39m • 4 changes
Arrives next day




16h 51m • 4 changes
Arrives next day




15h 40m • 4 changes




10h 51m • 4 changes




10h 51m • 4 changes




10h 51m • 4 changes
Arrives next day




16h 51m • 4 changes




10h 51m • 4 changes




10h 51m • 4 changes




10h 51m • 4 changes
Arrives next day




16h 51m • 4 changes
Want to know about travelling from Prague to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Brussels. However, there are services departing from Prague station and arriving at Brussels station via Plzen Hlavni Nadrazi. The journey, including transfers, takes approximately 13h 36m.
Prague to Brussels train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague to Brussels train services, operated by České dráhy (ČD), arrive at Brussels-Nord station.
Book your Prague to Brussels train tickets online with České dráhy (ČD) and Deutsche Bahn Intercity (DB IC).
The distance between Prague and Brussels is 717.3 km. The road distance is 975 km.
You can take a train from Praha Hlavni Nadrazi to Brussels-Nord via Plzen Hlavni Nadrazi, Cheb, Nuernberg Hbf, Nürnberg Hbf, and Frankfurt in around 12h 37m.