The average train between Mainz and Czechia takes 10h 12m and the fastest train takes 8h 17m. The train service runs several times per day from Mainz to Czechia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Czechia. The earliest departure is at 4:04 AM at night, and the last departure from Mainz is at 7:14 PM which arrives into Czechia at 10:21 AM. All services require a transfer at Frankfurt and take an average of 10h 12m. The schedules shown below are for the next available departures.



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9h 7m • 3 changesWant to know about travelling from Mainz to Czechia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Czechia. However, there are services departing from Frankfurt station and arriving at Praha Hlavni Nadrazi station via Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 10h 12m.
Mainz to Czechia train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz to Czechia train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
Book your Mainz to Czechia train tickets online with Omio and 12go.asia.
The distance between Mainz and Czechia is 506.5 km. The road distance is 541 km.
You can take a train from Mainz, Römisches Theater to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 6m.