Mainz to Brussels Trains

Mainz to Brussels trains

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Trip Overview

The average train between Mainz and Brussels takes 4h 58m and the fastest train takes 4h 15m. The train service runs several times per day from Mainz to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 58m
Duration: 401 km
Distance: €84
Average price: Every 3 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Köln Hbftrain 55 / ...
Take the train from Köln Hbf to Bruxelles Miditrain 79

4h 47m

€55–289

Mainz to Brussels train times

Trains run every 3 hours between Mainz and Brussels. The earliest departure is at 3:49 AM at night, and the last departure from Mainz is at 9:20 PM which arrives into Brussels at 9:35 AM. All services require a transfer, and take on average 4h 58m. The schedules shown below are for the next available departures.

Departing Friday, July 31, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
Show more

Departing Saturday, August 1, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
Show more

Departing Sunday, August 2, 2026

3:49 AM → 9:35 AM
5h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
Show more

Departing Monday, August 3, 2026

7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
1:20 PM → 5:35 PM
4h 15m • 1 change
Show more

Departing Tuesday, August 4, 2026

7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
1:20 PM → 5:35 PM
4h 15m • 1 change
Show more

Departing Wednesday, August 5, 2026

7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
1:20 PM → 5:35 PM
4h 15m • 1 change
Show more

Departing Thursday, August 6, 2026

7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
11:20 AM → 3:35 PM
4h 15m • 1 change
1:20 PM → 5:35 PM
4h 15m • 1 change

Frequently asked questions

Want to know about travelling from Mainz to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.