There are 6 ways to get from Mainz to Brussels by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Frankfurt
best- Take the train from Frankfurt to Brussels-Nord79
4h 2m€57–142Bus
cheapest- Take the bus from Mainz central train station to Brussels-North train stationN1310
5h 45m€24–50Night train
- Take the night train from Mainz Hbf to Brussels-NordNj
4h 53m€40–261Drive 365.9 km
- Drive from Mainz to Brussels365.9 km
3h 39m€56–80Train
- Take the train from Mainz Hbf to Bruxelles-NordNj
4h 53m€30–50Fly
- Fly from Frankfurt (FRA) to Brussels Airport (BRU)FRA - BRU
3h 45m€85–222
Mainz to Brussels by train
Questions & Answers
The cheapest way to get from Mainz to Brussels is to bus which costs €24 - €50 and takes 5h 45m.
The fastest way to get from Mainz to Brussels is to drive which takes 3h 39m and costs €55 - €80.
Yes, there is a direct bus departing from Mainz central train station station and arriving at Brussels-North train station station. Services depart once daily, and operate every day. The journey takes approximately 5h 45m.
Yes, there is an overnight train departing from Mainz Hbf and arriving at Brussels-Nord. This train operates Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. The journey takes approximately 4h 53m.
The distance between Mainz and Brussels is 411 km. The road distance is 365.9 km.
The best way to get from Mainz to Brussels without a car is to train via Frankfurt which takes 4h 2m and costs €55 - €150.
It takes approximately 4h 2m to get from Mainz to Brussels, including transfers.
Mainz to Brussels bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Brussels is to train via Frankfurt which takes 4h 2m and costs €55 - €150. Alternatively, you can bus, which costs €24 - €50 and takes 5h 45m, you could also fly, which costs €85 - €230 and takes 3h 45m.
What companies run services between Mainz, Germany and Brussels, Belgium?
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Brussels-Nord every 3 hours. Tickets cost €50–130 and the journey takes 2h 38m. Alternatively, FlixBus operates a bus from Mainz central train station to Brussels-North train station once daily. Tickets cost €24–50 and the journey takes 5h 45m.
- Website
- brusselsairlines.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €70–160
- Website
- lufthansa.com
Flights from Frankfurt to Brussels Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- €70–160
- Website
- klm.com
Flights from Frankfurt to Brussels Airport via Amsterdam Schiphol
- Ave. Duration
- 3h
- When
- Monday to Friday
- Estimated price
- €40–260
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Frankfurt to Brussels-Nord
- Ave. Duration
- 2h 38m
- Frequency
- Every 3 hours
- Estimated price
- €50–130
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Mainz Hbf to Brussels-Nord
- Ave. Duration
- 4h 53m
- Frequency
- 4 times a week
- Estimated price
- €40–261
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €259–261
- Couchette Carriage
- €130–160
- Seating Carriage
- €40–55
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Mainz Hbf to Bruxelles-Nord
- Ave. Duration
- 4h 53m
- Frequency
- Twice a week
- Estimated price
- €30–50
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €30–50
- 1st Class
- €50–75
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mainz central train station to Brussels-North train station
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- €24–50
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Belgium
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Mainz to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Mainz to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Brussels-Nord station.
Yes, the driving distance between Mainz to Brussels is 366 km. It takes approximately 3h 39m to drive from Mainz to Brussels.
Book your Mainz to Brussels train tickets online with Omio.
Book your Mainz to Brussels bus tickets online with Omio and FlixBus.
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