The average train between Mainz and Dresden takes 5h 30m and the fastest train takes 5h 8m. The train service runs several times per day from Mainz to Dresden. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Dresden. The earliest departure is at 5:35 AM in the morning, and the last departure from Mainz is at 6:35 PM which arrives into Dresden at 11:45 PM. All services require a transfer, and take on average 5h 30m. The schedules shown below are for the next available departures.

6h 8m • 1 change

5h 57m • 1 change

6h 8m • 1 change

6h 8m • 1 change

5h 8m • 1 change

5h 9m • 1 change

5h 8m • 1 change

5h 8m • 1 change

5h 9m • 1 change

5h 10m • 1 change

5h 9m • 1 change

5h 9m • 1 change

5h 9m • 1 change

5h 10m • 1 change

5h 9m • 1 change

5h 9m • 1 change

5h 9m • 1 change

5h 10m • 1 change

5h 9m • 1 change

5h 9m • 1 change

5h 8m • 1 change

5h 9m • 1 change

5h 8m • 1 change

5h 8m • 1 change
Want to know about travelling from Mainz to Dresden? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Dresden. However, there are services departing from Mainz station and arriving at Dresden station via Dresden Hauptbahnhof. The journey, including transfers, takes approximately 5h 30m.
Mainz to Dresden train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Dresden train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Dresden Hauptbahnhof station.
Book your Mainz to Dresden train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Süwex.
The distance between Mainz and Dresden is 403.7 km. The road distance is 528 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Dresden Hauptbahnhof hourly. Tickets cost €90–350 and the journey takes 4h 24m.