Istres to Lyon Trains

Istres to Lyon trains

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Trip Overview

The average train between Istres and Lyon takes 5h 4m and the fastest train takes 3h 10m. The train service runs several times per day from Istres to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 4m
Duration: 310 km
Distance: €67
Average price: Every 4 hours
Frequency

Train via Avignon

best

Take the train from Miramas to Avignon Centretrain Ter
Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv

3h 5m

€41–101

Istres to Lyon train times

Trains run every 4 hours between Istres and Lyon. The earliest departure is at 8:16 AM in the morning, and the last departure from Istres is at 9:49 PM which arrives into Lyon at 8:40 AM. All services require a transfer at Miramas and take an average of 5h 4m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

9:49 PM → 8:40 AM
Arrives next day
10h 51m • 3 changes

Departing Friday, October 23, 2026

8:16 AM → 11:28 AM
3h 12m • 3 changes
10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 3:28 PM
3h 12m • 3 changes
2:16 PM → 5:51 PM
3h 35m • 3 changes
Show more

Departing Saturday, October 24, 2026

10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 3:28 PM
3h 12m • 3 changes
2:16 PM → 5:40 PM
3h 24m • 3 changes
3:44 PM → 10:01 PM
6h 17m • 3 changes
Show more

Departing Sunday, October 25, 2026

10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 3:28 PM
3h 12m • 3 changes
2:16 PM → 5:51 PM
3h 35m • 3 changes
3:44 PM → 6:54 PM
3h 10m • 3 changes
Show more

Departing Monday, October 26, 2026

8:16 AM → 11:28 AM
3h 12m • 3 changes
10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 3:28 PM
3h 12m • 3 changes
2:16 PM → 5:51 PM
3h 35m • 3 changes
Show more

Departing Tuesday, October 27, 2026

8:16 AM → 11:28 AM
3h 12m • 3 changes
10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 4:20 PM
4h 4m • 3 changes
2:16 PM → 5:51 PM
3h 35m • 3 changes
Show more

Departing Wednesday, October 28, 2026

8:16 AM → 11:28 AM
3h 12m • 3 changes
10:16 AM → 1:53 PM
3h 37m • 3 changes
12:16 PM → 4:20 PM
4h 4m • 3 changes
2:16 PM → 5:51 PM
3h 35m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Istres to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.