The average train between Istres and Nyon takes 9h and the fastest train takes 5h 38m. The train service runs several times per day from Istres to Nyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Istres and Nyon. The earliest departure is at 8:16 AM in the morning, and the last departure from Istres is at 9:49 PM which arrives into Nyon at 1:07 PM. All services require a transfer at Miramas and take an average of 9h. The schedules shown below are for the next available departures.





6h 51m • 5 changes





5h 38m • 5 changes





6h 51m • 5 changes





7h 8m • 5 changes





6h 51m • 5 changes





6h 47m • 5 changes





5h 38m • 5 changes





7h 8m • 5 changes





6h 51m • 5 changes





6h 47m • 5 changes





6h 51m • 5 changes





7h 8m • 5 changes





6h 51m • 5 changes





6h 47m • 5 changes





6h 51m • 5 changes





7h 8m • 5 changes





6h 51m • 5 changes





6h 47m • 5 changes





5h 38m • 5 changes





7h 8m • 5 changes





6h 51m • 5 changes





6h 47m • 5 changes





5h 38m • 5 changes





6h 51m • 5 changes
Want to know about travelling from Istres to Nyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Istres to Nyon. However, there are services departing from Istres station and arriving at Nyon station via Avignon Centre. The journey, including transfers, takes approximately 9h.
Istres to Nyon train services, operated by Zou! Lignes Express Régionales, depart from Miramas station.
Istres to Nyon train services, operated by Zou! Lignes Express Régionales, arrive at Geneve station.
Book your Istres to Nyon train tickets online with Zou! Lignes Express Régionales, TGV inOui and 2 other operators.
The distance between Istres and Nyon is 334 km. The road distance is 494 km.
You can take a train from Istres to Nyon via Miramas, Avignon Centre, Avignon Tgv, Lyon Part Dieu, and Genève in around 6h 6m.