There are 7 ways to get from Istres to Lyon by train (TGV, Trenitalia), bus, car, train, plane, or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Avignon
best- Take the train from Miramas to Avignon Centretrain Ter
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
3h 5m€42–122Rideshare
cheapest- Take the rideshare from Istres to Lyon284.3 km
3h 18m€15–20Bus
- Take the bus from Salon-de-Provence to Avignonbus N789
- Take the bus from Avignon to Lyonbus FlixBus N1135 / ...
5h 47m€21–42Drive 282.4 km
- Drive from Istres to Lyoncar 282.4 km
2h 51m€44–63Train, fly
- Take the train from Istres to Miramastrain
- Take the train from Miramas to Vitrolles Aeroport Marseilletrain
- Fly from Marseille Provence Airport (MRS) to Lyon–Saint Exupéry Airport (LYS)plane MRS - LYS
3h 32m€98–227Train
- Take the train from Miramas to Lyon Part Dieutrain Ter
4h 28m€50–150Train via Livron-sur-Drôme
- Take the train from Miramas to Livrontrain K34
- Take the train from Livron to Lyon Jean Macétrain K24
5h 38m€75–151
Istres to Lyon by train
Questions & Answers
The cheapest way to get from Istres to Lyon is to rideshare which costs €15 - €20 and takes 3h 18m.
The fastest way to get from Istres to Lyon is to drive which takes 2h 51m and costs €40 - €65.
No, there is no direct bus from Istres to Lyon. However, there are services departing from Les Carmes and arriving at Lyon via Salon-de-Provence and Avignon. The journey, including transfers, takes approximately 5h 47m.
No, there is no direct train from Istres to Lyon. However, there are services departing from Istres and arriving at Lyon Part Dieu via Miramas, Avignon Centre and Avignon Tgv. The journey, including transfers, takes approximately 3h 5m.
The distance between Istres and Lyon is 310 km. The road distance is 282.4 km.
The best way to get from Istres to Lyon without a car is to train via Avignon which takes 3h 5m and costs €40 - €130.
It takes approximately 3h 5m to get from Istres to Lyon, including transfers.
Istres to Lyon bus services, operated by FlixBus, depart from Salon-de-Provence station.
Istres to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Miramas station.
The best way to get from Istres to Lyon is to train via Avignon which takes 3h 5m and costs €40 - €130. Alternatively, you can bus, which costs €21 - €45 and takes 5h 47m.
What companies run services between Istres, France and Lyon, France?
You can take a train from Istres to Lyon Part Dieu via Miramas, Avignon Centre, and Avignon Tgv in around 3h 5m. Alternatively, you can take a bus from Les Carmes to Lyon via Salon-de-Provence and Avignon in around 5h 47m.
- Website
- airfrance.com
Flights from Marseille Provence Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 55 min
- When
- Monday to Thursday
- Estimated price
- €30–250
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Miramas to Avignon Centre
- Ave. Duration
- 1h 10m
- Frequency
- Every 30 minutes
- Estimated price
- €11–23
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €35–75
- Website
- Oui.SNCF
Train from Istres to Miramas
- Ave. Duration
- 9 min
- Frequency
- Hourly
- Estimated price
- €1–4
- Website
- Oui.SNCF
Train from Miramas to Vitrolles Aeroport Marseille
- Ave. Duration
- 21 min
- Frequency
- Every 20 minutes
- Estimated price
- €5–11
- Website
- Oui.SNCF
Train from Miramas to Lyon Part Dieu
- Ave. Duration
- 3h 13m
- Frequency
- Every 4 hours
- Estimated price
- €50–100
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Miramas to Avignon Centre
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- Zou! Lignes Express Régionales
Train from Istres to Miramas
- Ave. Duration
- 9 min
- Frequency
- Hourly
- Estimated price
- €2–6
- Website
- Zou! Lignes Express Régionales
Train from Miramas to Vitrolles Aeroport Marseille
- Ave. Duration
- 23 min
- Frequency
- Every 30 minutes
- Estimated price
- €7–16
- Website
- Zou! Lignes Express Régionales
Train from Miramas to Lyon Part Dieu
- Ave. Duration
- 3h 13m
- Frequency
- 3 times a day
- Estimated price
- €75–150
- Website
- Zou! Lignes Express Régionales
Train from Miramas to Livron
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- €45–90
- Website
- Zou! Lignes Express Régionales
Train from Livron to Lyon Jean Macé
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- €30–65
- Website
- Zou! Lignes Express Régionales
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Miramas to Avignon Centre
- Ave. Duration
- 40 min
- Frequency
- 4 times a day
- Estimated price
- €14–23
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €45–75
- Website
- TGV inOui
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- €28–50
- Website
- Trenitalia
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €35–80
- Website
- Belgian Railways
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Salon-de-Provence to Avignon
- Ave. Duration
- 40 min
- Frequency
- 5 times a week
- Estimated price
- €4–7
- Website
- Flixbus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- €17–29
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- €19–35
- Website
- BlaBlaCar Bus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Istres to Lyon
- Ave. Duration
- 3h 18m
- Frequency
- Once daily
- Estimated price
- €15–20
- Schedules at
- BlaBlaCar
Want to know more about travelling around France
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More Questions & Answers
Istres to Lyon bus services, operated by FlixBus, arrive at Avignon station.
Istres to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Avignon Centre station.
Yes, the driving distance between Istres to Lyon is 282 km. It takes approximately 2h 51m to drive from Istres to Lyon.
Book your Istres to Lyon train tickets online with Omio.
There are 4086+ hotels available in Lyon.
Check out Blablacar's carpooling service for rideshare options between Istres and Lyon. A great option if you don't have a driver's licence or want to avoid public transport.


























