Isernia to Tuscany Trains

Trip Overview

The average train between Isernia and Tuscany takes 5h 38m and the fastest train takes 4h 19m. The train service runs several times per day from Isernia to Tuscany. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 38m
Duration: 447 km
Distance: €67
Average price: 5 times a day
Frequency

Train (Trenitalia)

best

Take the train from Isernia to Roma Terminitrain Re
Take the train from Roma Termini to Firenze S.M.N.train Fr

4h 13m

€51–118

Isernia to Tuscany train times

Trains run 5 times a day between Isernia and Tuscany. The earliest departure is at 6:35 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Tuscany at 6:46 AM. All services require a transfer, and take on average 5h 38m. The schedules shown below are for the next available departures.

Departing Friday, August 21, 2026

6:00 PM → 11:05 PM
5h 5m • 1 change
8:35 PM → 6:46 AM
Arrives next day
10h 11m • 1 change

Departing Saturday, August 22, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:03 PM → 7:46 PM
4h 43m • 1 change
6:00 PM → 11:20 PM
5h 20m • 1 change
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Departing Sunday, August 23, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:19 PM → 7:46 PM
4h 27m • 1 change
5:27 PM → 9:46 PM
4h 19m • 1 change
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Departing Monday, August 24, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:03 PM → 7:46 PM
4h 43m • 1 change
6:00 PM → 11:05 PM
5h 5m • 1 change
Show more

Departing Tuesday, August 25, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:03 PM → 7:46 PM
4h 43m • 1 change
6:00 PM → 11:05 PM
5h 5m • 1 change
Show more

Departing Wednesday, August 26, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:03 PM → 7:46 PM
4h 43m • 1 change
6:00 PM → 11:05 PM
5h 5m • 1 change
Show more

Departing Thursday, August 27, 2026

6:35 AM → 11:01 AM
4h 26m • 1 change
8:38 AM → 1:11 PM
4h 33m • 1 change
3:03 PM → 7:46 PM
4h 43m • 1 change
6:00 PM → 11:05 PM
5h 5m • 1 change

Frequently asked questions

Want to know about travelling from Isernia to Tuscany? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.