The average train between Isernia and Colosseum takes 2h 24m and the fastest train takes 2h 14m. The train service runs several times per day from Isernia to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Isernia and Colosseum. The earliest departure is at 6:40 AM in the morning, and the last departure from Isernia is at 8:35 PM which arrives into Colosseum at 11:04 PM. All services require a transfer at Rome Termini and take an average of 2h 24m. The schedules shown below are for the next available departures.

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Want to know about travelling from Isernia to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Isernia to Colosseum. However, there are services departing from Isernia station and arriving at Colosseum station via Roma Termini. The journey, including transfers, takes approximately 2h 24m.
Isernia to Colosseum train services, operated by Trenitalia, depart from Isernia station.
Isernia to Colosseum train services, operated by Trenitalia, arrive at Roma Termini station.
The distance between Isernia and Colosseum is 148.2 km. The road distance is 188 km.
Trenitalia operates a train from Isernia to Roma Termini 5 times a day. Tickets cost €23–40 and the journey takes 2h 25m.