The average train between Genoa and Mainz takes 12h 18m and the fastest train takes 10h 9m. The train service runs several times per day from Genoa to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Genoa and Mainz. The earliest departure is at 8:10 AM in the morning, and the last departure from Genoa is at 8:10 PM which arrives into Mainz at 3:18 PM. All services require a transfer at Milano Centrale and take an average of 12h 18m. The schedules shown below are for the next available departures.



10h 33m • 3 changes


10h 9m • 3 changes


11h 43m • 3 changesArrives next day



15h 28m • 3 changes


10h 33m • 3 changes


10h 9m • 3 changesArrives next day



19h 8m • 3 changes


10h 33m • 3 changes


10h 9m • 3 changes


11h 43m • 3 changesArrives next day



15h 28m • 3 changes


10h 33m • 3 changes


10h 9m • 3 changes


11h 43m • 3 changesArrives next day



15h 28m • 3 changesWant to know about travelling from Genoa to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Genoa to Mainz. However, there are services departing from Genoa station and arriving at Mainz station via Milano Centrale. The journey, including transfers, takes approximately 12h 18m.
Genoa to Mainz train services, operated by Trenitalia Intercity, depart from Genova Brignole station.
Genoa to Mainz train services, operated by Trenitalia Intercity, arrive at Mainz, Hauptbahnhof station.
Book your Genoa to Mainz train tickets online with Trenitalia Intercity, Trenitalia EuroCity and 3 other operators.
The distance between Genoa and Mainz is 622.4 km. The road distance is 827 km.
You can take a train from Genova Brignole to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 10h 35m.