The average train between Manchester and Mainz takes 10h 26m and the fastest train takes 8h 9m. The train service runs several times per day from Manchester to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manchester and Mainz. The earliest departure is at 6:30 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Mainz at 1:44 PM. All services require a transfer at London Euston and take an average of 10h 26m. The schedules shown below are for the next available departures.



8h 14m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 14m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 14m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 14m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 13m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changes


8h 9m • 3 changesWant to know about travelling from Manchester to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Mainz. However, there are services departing from Manchester Piccadilly station and arriving at Frankfurt station via London Euston station and Brussel-Zuid / Bruxelles-Midi station. The journey, including transfers, takes approximately 10h 26m.
Manchester to Mainz train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Manchester to Mainz train tickets online with Omio.
The distance between Manchester and Mainz is 820.9 km.
You can take a train from Manchester Piccadilly to Mainz, Römisches Theater via London Euston, London St Pancras Intl, Brussels-Midi, Bruxelles Midi, and Frankfurt in around 9h 31m.