The average train between Milan and Mainz takes 9h 8m and the fastest train takes 8h 8m. The train service runs several times per day from Milan to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Milan and Mainz. The earliest departure is at 7:10 AM in the morning, and the last departure from Milan is at 6:05 PM which arrives into Mainz at 8:43 AM. All services require a transfer at Basel SBB and take an average of 9h 8m. The schedules shown below are for the next available departures.


8h 8m • 2 changes


8h 33m • 2 changes


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8h 43m • 2 changes


8h 8m • 2 changes


8h 33m • 2 changes


8h 8m • 2 changes


8h 43m • 2 changes


8h 8m • 2 changes


8h 33m • 2 changes


8h 8m • 2 changes


8h 43m • 2 changes


8h 8m • 2 changes


8h 33m • 2 changes


8h 8m • 2 changes


8h 43m • 2 changes


8h 8m • 2 changes


8h 33m • 2 changes


8h 8m • 2 changes


8h 43m • 2 changes
Want to know about travelling from Milan to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Mainz. However, there are services departing from Milan station and arriving at Mainz station via Basel Sbb. The journey, including transfers, takes approximately 9h 8m.
Milan to Mainz train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
Milan to Mainz train services, operated by Trenitalia EuroCity, arrive at Mainz, Hauptbahnhof station.
Book your Milan to Mainz train tickets online with Trenitalia EuroCity, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Milan and Mainz is 507.2 km. The road distance is 685 km.
You can take a train from Milano Centrale to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 7h 44m.