Train Desio to Mendrisio from CHF 15 | Tickets & Timetables

Trip Overview

The average train between Desio and Mendrisio takes 53 min and the fastest train takes 49 min. There is a train service every few hours from Desio to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

53 min
Duration: 40 km
Distance: CHF 15
Average price: Hourly
Frequency

Train

best

Take the train from Seregno to Mendrisiotrain Re80 / ...

1h 2m

CHF 5–42

Desio to Mendrisio train times

Trains run hourly between Desio and Mendrisio. The earliest departure is at 5:52 AM in the morning, and the last departure from Desio is at 11:06 PM which arrives into Mendrisio at 12:30 AM. All services require a transfer, and take on average 53 min. The schedules shown below are for the next available departures.

Departing Tuesday, July 7, 2026

5:52 AM → 6:41 AM
49 min • 1 change
6:52 AM → 7:41 AM
49 min • 1 change
7:52 AM → 8:41 AM
49 min • 1 change
8:52 AM → 9:41 AM
49 min • 1 change
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Departing Wednesday, July 8, 2026

5:52 AM → 6:41 AM
49 min • 1 change
6:52 AM → 7:41 AM
49 min • 1 change
7:52 AM → 8:41 AM
49 min • 1 change
8:52 AM → 9:41 AM
49 min • 1 change
Show more

Departing Thursday, July 9, 2026

5:52 AM → 6:41 AM
49 min • 1 change
6:52 AM → 7:41 AM
49 min • 1 change
7:52 AM → 8:41 AM
49 min • 1 change
8:52 AM → 9:41 AM
49 min • 1 change
Show more

Frequently asked questions

Want to know about travelling from Desio to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.