Rome2Rio

Desio to Rome trains

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Trip Overview

The average train between Desio and Rome takes 4h 53m and the fastest train takes 4h 2m. The train service runs several times per day from Desio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 53m
Duration
578 km
Distance
€95
Average price
Every 3 hours
Frequency

Desio to Rome train times

Trains run every 3 hours between Desio and Rome. The earliest departure is at 6:23 AM in the morning, and the last departure from Desio is at 7:23 PM which arrives into Rome at 9:19 AM. All services require a transfer at niguarda and take an average of 4h 53m. The schedules shown below are for the next available departures.

Departing Monday, November 16, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Tuesday, November 17, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Wednesday, November 18, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Thursday, November 19, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Departing Friday, November 20, 2026

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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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    TrenordItaloTreno4h 2m • 1 change
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Frequently asked questions

Want to know about travelling from Desio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Desio to Rome.ExpandLaunch map view
  • Distance: 577.9 km
  • Duration: 4h 53m

What companies run services between Desio, Italy and Rome, Italy?

Trenitalia Frecce operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €75–130 and the journey takes 3h 4m. ItaloTreno also services this route 4 times a day.

Operators