The average train between Desio and Rome takes 4h 57m and the fastest train takes 4h 2m. The train service runs several times per day from Desio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Desio and Rome. The earliest departure is at 6:23 AM in the morning, and the last departure from Desio is at 7:23 PM which arrives into Rome at 9:19 AM. All services require a transfer at Rho Fiera Milano and take an average of 4h 57m. The schedules shown below are for the next available departures.

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Want to know about travelling from Desio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Desio to Rome. However, there are services departing from Desio station and arriving at Rome station via Rho Fiera Milano. The journey, including transfers, takes approximately 4h 57m.
Desio to Rome train services, operated by Trenord, depart from Desio station.
Desio to Rome train services, operated by Trenord, arrive at Roma Termini station.
Book your Desio to Rome train tickets online with Trenord and ItaloTreno.
The distance between Desio and Rome is 490.8 km. The road distance is 598 km.
You can take a train from Desio to Roma Termini via Rho Fiera Milano and Milano Rogoredo in around 4h.