The average train between Zurich and Mainz takes 5h 15m and the fastest train takes 4h 10m. The train service runs several times per day from Zurich to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Zurich and Mainz. The earliest departure is at 7:59 AM in the morning, and the last departure from Zurich is at 9:59 PM which arrives into Mainz at 5:38 AM. All services require a transfer at Basel SBB and take an average of 5h 15m. The schedules shown below are for the next available departures.


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4h 44m • 2 changesWant to know about travelling from Zurich to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Zurich to Mainz. However, there are services departing from Zürich HB station and arriving at Mainz, Hauptbahnhof station via Basel SBB station and Mannheim, Hauptbahnhof station. The journey, including transfers, takes approximately 5h 15m.
Zurich to Mainz train services, operated by SBB GmbH, depart from Zürich HB station.
Zurich to Mainz train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mainz, Hauptbahnhof station.
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The distance between Zurich and Mainz is 291.7 km. The road distance is 372 km.
You can take a train from Zürich HB to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 5h 5m.