The average train between Lille and Mainz takes 6h 28m and the fastest train takes 4h 42m. The train service runs several times per day from Lille to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Lille and Mainz. The earliest departure is at 7:04 AM in the morning, and the last departure from Lille is at 10:16 PM which arrives into Mainz at 10:44 AM. All services require a transfer at Brussels-Midi and take an average of 6h 28m. The schedules shown below are for the next available departures.


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5h 14m • 2 changes
Want to know about travelling from Lille to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lille to Mainz. However, there are services departing from Lille station and arriving at Mainz station via Brussel-Zuid / Bruxelles-Midi. The journey, including transfers, takes approximately 6h 28m.
Lille to Mainz train services, operated by TGV inOui, depart from Lille Europe station.
Lille to Mainz train services, operated by TGV inOui, arrive at Frankfurt station.
Book your Lille to Mainz train tickets online with TGV inOui, Belgian Railways (NMBS/SNCB) and 3 other operators.
The distance between Lille and Mainz is 377.6 km. The road distance is 520 km.
You can take a train from Lille Europe to Mainz, Römisches Theater via Brussels-Midi, Bruxelles Midi, and Frankfurt in around 4h 50m.