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Amsterdam to Mainz trains

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Trip Overview

The average train between Amsterdam and Mainz takes 5h and the fastest train takes 4h 40m. The train service runs several times per day from Amsterdam to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h
Duration
452 km
Distance
€65
Average price
Every 4 hours
Frequency

Amsterdam to Mainz train times

Trains run every 4 hours between Amsterdam and Mainz. The earliest departure is at 6:01 AM in the morning, and the last departure from Amsterdam is at 6:01 PM which arrives into Mainz at 10:44 PM. All services require a transfer at Frankfurt(M) Flughafen Fernbf and take an average of 5h. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
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    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change

Departing Wednesday, November 11, 2026

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    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
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    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  • Show more

Departing Thursday, November 12, 2026

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    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  • Show more

Departing Friday, November 13, 2026

  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 22m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 22m • 1 change
  • Show more

Departing Sunday, November 15, 2026

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    Nederlandse Spoorwegen (NS)vlexx4h 40m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 22m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 22m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)vlexx4h 43m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  •  → 

    Nederlandse Spoorwegen (NS)Deutsche Bahn Regio (DB Regional)5h 21m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Amsterdam to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Amsterdam to Mainz.ExpandLaunch map view
  • Distance: 452.2 km
  • Duration: 5h

What companies run services between Amsterdam, Netherlands and Mainz, Germany?

Nederlandse Spoorwegen (NS) operates a train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €45–85 and the journey takes 3h 36m.

Operators