There are 8 ways to get from Amsterdam to Mainz by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Frankfurt
best- Take the train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbftrain Ice
4h 16mDrive 422.3 km
cheapest- Drive from Amsterdam to Mainzcar 422.3 km
4h 11m€75–108Bus
- Take the bus from Amsterdam Sloterdijk to Düsseldorf central bus stationbus N61 / ...
- Take the bus from Düsseldorf central bus station to Wiesbaden central train stationbus FlixBus 027
7h 34mFly Amsterdam Airport Schiphol to Frankfurt
- Fly from Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA)plane AMS - FRA
3h 58m€110–260Train
- Take the train from Amsterdam Centraal to Mainz Hbftrain Nightjet
5h 25mTrain via Düsseldorf
- Take the train from Amsterdam Zuid to Venlotrain
- Take the train from Venlo to Neuss Hbftrain
- Take the train from Köln Messe/Deutz Bf to Mainz, Hauptbahnhoftrain
8h 16mTrain to Düsseldorf International Airport, fly to Frankfurt
- Take the train from Amsterdam Centraal to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Frankfurt (FRA)plane DUS - FRA
5h 5mFly Amsterdam Airport Schiphol to Düsseldorf International Airport, train
- Fly from Amsterdam Airport Schiphol (AMS) to Düsseldorf International Airport (DUS)plane AMS - DUS
- Take the train from Düsseldorf Hbf to Frankfurttrain
4h 29m
Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA) flights
Questions & Answers
The cheapest way to get from Amsterdam to Mainz is to drive which costs €70 - €110 and takes 4h 11m.
The fastest way to get from Amsterdam to Mainz is to fly which takes 3h 58m and costs €110 - €260.
No, there is no direct bus from Amsterdam to Mainz. However, there are services departing from Amsterdam Sloterdijk and arriving at Mainz, Münsterplatz via Düsseldorf central bus station and Wiesbaden Mainzer Straße/1.Ring. The journey, including transfers, takes approximately 7h 34m.
Yes, there is a direct train departing from Amsterdam Centraal and arriving at Mainz Hbf. Services depart once daily, and operate every day. The journey takes approximately 5h 25m.
The distance between Amsterdam and Mainz is 450 km. The road distance is 422.3 km.
The best way to get from Amsterdam to Mainz without a car is to train via Frankfurt which takes 4h 16m and costs .
It takes approximately 4h 16m to get from Amsterdam to Mainz, including transfers.
Amsterdam to Mainz bus services, operated by FlixBus-eu, depart from Amsterdam Sloterdijk station.
Amsterdam to Mainz train services, operated by NS Reizigers, depart from Amsterdam Centraal station.
The best way to get from Amsterdam to Mainz is to train via Frankfurt which takes 4h 16m and costs . Alternatively, you can bus, which costs and takes 7h 34m, you could also fly, which costs €110 - €260 and takes 3h 58m.
What companies run services between Amsterdam, Netherlands and Mainz, Germany?
NS Reizigers operates a train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf every 4 hours, and the journey takes 3h 40m. NS Int also services this route every 4 hours. Alternatively, you can take a bus from Amsterdam Sloterdijk to Mainz, Münsterplatz via Düsseldorf central bus station, Wiesbaden central train station, and Wiesbaden Mainzer Straße/1.Ring in around 7h 34m.
- Website
- lufthansa.com
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €110–270
Flights from Düsseldorf International Airport to Frankfurt
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €27–220
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €35–270
Flights from Amsterdam Airport Schiphol to Düsseldorf International Airport
- Ave. Duration
- 48 min
- When
- Every day
- Estimated price
- €30–260
- Website
- airdolomiti.it
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €150–270
- Website
- lufthansa-city.com
Flights from Düsseldorf International Airport to Frankfurt
- Ave. Duration
- 50 min
- When
- Thursday and Friday
- Estimated price
- €27–220
- Website
- condor.com
Flights from Düsseldorf International Airport to Frankfurt
- Ave. Duration
- 50 min
- When
- Wednesday
- Estimated price
- €70–210
- Website
- ns.nl
Train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 3h 40m
- Frequency
- Every 4 hours
- Schedules at
- ns.nl
Train from Amsterdam Centraal to Duesseldorf Hbf
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Schedules at
- ns.nl
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 27m
- Frequency
- Every 4 hours
- Schedules at
- ns.nl
- Website
- nsinternational.nl
Train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 4h 28m
- Frequency
- Every 4 hours
- Schedules at
- nsinternational.nl
Train from Amsterdam Centraal to Mainz Hbf
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Schedules at
- nsinternational.nl
Train from Amsterdam Centraal to Duesseldorf Hbf
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Schedules at
- nsinternational.nl
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Schedules at
- nsinternational.nl
- Website
- eurobahn.de
Train from Venlo to Neuss Hbf
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Schedules at
- eurobahn.de
- Website
- global.flixbus.com
Bus from Amsterdam Sloterdijk to Düsseldorf central bus station
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Schedules at
- global.flixbus.com
Bus from Düsseldorf central bus station to Wiesbaden central train station
- Ave. Duration
- 3h 20m
- Frequency
- 5 times a week
- Schedules at
- global.flixbus.com
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More Questions & Answers
Amsterdam to Mainz bus services, operated by FlixBus-eu, arrive at Düsseldorf central bus station.
Amsterdam to Mainz train services, operated by NS Reizigers, arrive at Frankfurt(M) Flughafen Fernbf station.
Yes, the driving distance between Amsterdam to Mainz is 422 km. It takes approximately 4h 11m to drive from Amsterdam to Mainz.
Book your Amsterdam to Mainz train tickets online with Omio.
There are 414+ hotels available in Mainz.



