There are 9 ways to get from Amsterdam to Mainz by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbftrain Ice / ...
4h 13m€51–110Bus
cheapest- Take the bus from Amsterdam Sloterdijk to Frankfurt central train stationbus N61 / ...
7h 45m€33–56Drive 422.3 km
- Drive from Amsterdam to Mainzcar 422.3 km
4h 10m€75–108Fly Amsterdam Airport Schiphol to Frankfurt
- Fly from Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA)plane AMS - FRA
3h 58m€127–308Train via Cologne
- Take the train from Amsterdam Centraal to Köln Hbftrain Ice / ...
- Take the train from Köln Hbf to Mainz, Hauptbahnhoftrain 43N / ...
5h 22m€47–141Train #2
- Take the train from Amsterdam Centraal to Mainz Hbftrain Nightjet
5h 25m€45–110Train, bus
- Take the train from Amsterdam Centraal to Nijmegentrain
- Take the bus from Nijmegen Centraal Station to Emmerich Bahnhofbus
- Take the train from Emmerich Bahnhof to Mainz, Hauptbahnhoftrain 43N
7h 7m€69–178Train to Düsseldorf International Airport, fly to Frankfurt
- Take the train from Amsterdam Centraal to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Frankfurt (FRA)plane DUS - FRA
5h 2m€115–219Fly Amsterdam Airport Schiphol to Düsseldorf International Airport, train
- Fly from Amsterdam Airport Schiphol (AMS) to Düsseldorf International Airport (DUS)plane AMS - DUS
- Take the train from Düsseldorf Hbf to Frankfurttrain
4h 29m€150–405
Amsterdam to Mainz by train
Questions & Answers
The cheapest way to get from Amsterdam to Mainz is to bus which costs €30 - €60 and takes 7h 45m.
The fastest way to get from Amsterdam to Mainz is to fly which takes 3h 58m and costs €120 - €310.
No, there is no direct bus from Amsterdam to Mainz station. However, there are services departing from Amsterdam Sloterdijk and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 7h 45m.
Yes, there is a direct train departing from Amsterdam Centraal and arriving at Mainz Hbf. Services depart once daily, and operate every day. The journey takes approximately 5h 25m.
The distance between Amsterdam and Mainz is 450 km. The road distance is 422.3 km.
The best way to get from Amsterdam to Mainz without a car is to train which takes 4h 13m and costs €50 - €110.
It takes approximately 4h 13m to get from Amsterdam to Mainz, including transfers.
Amsterdam to Mainz bus services, operated by FlixBus, depart from Amsterdam Sloterdijk station.
Amsterdam to Mainz train services, operated by Nederlandse Spoorwegen (NS), depart from Amsterdam Centraal station.
The best way to get from Amsterdam to Mainz is to train which takes 4h 13m and costs €50 - €110. Alternatively, you can bus, which costs €30 - €60 and takes 7h 45m, you could also fly, which costs €120 - €310 and takes 3h 58m.
What companies run services between Amsterdam, Netherlands and Mainz, Germany?
Nederlandse Spoorwegen (NS) operates a train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €45–110 and the journey takes 3h 37m. Alternatively, FlixBus operates a bus from Amsterdam Sloterdijk to Frankfurt central train station every 2 hours. Tickets cost €30–55 and the journey takes 6h 5m.
- Website
- lufthansa.com
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €120–310
Flights from Düsseldorf International Airport to Frankfurt
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €28–240
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €40–300
Flights from Amsterdam Airport Schiphol to Düsseldorf International Airport
- Ave. Duration
- 48 min
- When
- Every day
- Estimated price
- €30–270
- Website
- airdolomiti.it
Flights from Amsterdam Airport Schiphol to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €160–270
- Website
- lufthansa-city.com
Flights from Düsseldorf International Airport to Frankfurt
- Ave. Duration
- 50 min
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €28–240
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Amsterdam Centraal to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 3h 37m
- Frequency
- Hourly
- Estimated price
- €45–110
- Website
- https://www.ns.nl/en
Train from Amsterdam Centraal to Köln Hbf
- Ave. Duration
- 3h 19m
- Frequency
- Every 3 hours
- Estimated price
- €27–65
- Website
- https://www.ns.nl/en
Train from Köln Hbf to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 47m
- Frequency
- Once daily
- Estimated price
- €19–45
- Website
- https://www.ns.nl/en
Train from Amsterdam Centraal to Mainz Hbf
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- €45–110
- Website
- https://www.ns.nl/en
Train from Amsterdam Centraal to Nijmegen
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- https://www.ns.nl/en
Train from Amsterdam Centraal to Duesseldorf Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Hourly
- Estimated price
- €23–55
- Website
- https://www.ns.nl/en
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- https://www.ns.nl/en
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Köln Hbf to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- €30–80
- Website
- https://int.bahn.de/en
Train from Emmerich Bahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://int.bahn.de/en
Train from Düsseldorf Hbf to Frankfurt
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- €35–90
- Website
- https://int.bahn.de/en
- Phone
- +49-261-98887070
- service@trans-regio.de
- Website
- mittelrheinbahn.de
Train from Köln Hbf to Mainz, Hauptbahnhof
- Ave. Duration
- 2h 59m
- Frequency
- Hourly
- Estimated price
- €30–45
- Schedules at
- mittelrheinbahn.de
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Amsterdam Sloterdijk to Frankfurt central train station
- Ave. Duration
- 6h 5m
- Frequency
- Every 2 hours
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
- Phone
- +49 2841 205-0
- nfo@niag-online.de
- Website
- niag.de
Bus from Nijmegen Centraal Station to Emmerich Bahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €6–10
- Schedules at
- niag.de
- Phone
- 0900 - 266 63 99
- Website
- breng.nl
Bus from Nijmegen Centraal Station to Emmerich Bahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €2
- Schedules at
- breng.nl
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Amsterdam to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Amsterdam to Mainz train services, operated by Nederlandse Spoorwegen (NS), arrive at Frankfurt(M) Flughafen Fernbf station.
Yes, the driving distance between Amsterdam to Mainz is 422 km. It takes approximately 4h 10m to drive from Amsterdam to Mainz.
Book your Amsterdam to Mainz train tickets online with Omio.
Book your Amsterdam to Mainz bus tickets online with FlixBus.
There are 414+ hotels available in Mainz.























