The average bus between Washington and St. Louis takes 21h 34m and the fastest bus takes 19h 25m. The bus service runs several times per day from Washington to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Washington and St. Louis. The earliest departure is at 1:50 AM at night, and the last departure from Washington is at 5:50 PM which arrives into St. Louis at 3:10 PM. All services require a transfer, and take on average 21h 34m. The schedules shown below are for the next available departures.
Arrives next day

18h 25m • 1 change
Arrives next day

21h 20m • 1 change

21h 25m • 1 change
Arrives next day

18h 25m • 1 change
Arrives next day

21h 20m • 1 change

21h 25m • 1 change
Arrives next day

18h 25m • 1 change
Arrives next day

21h 20m • 1 change

21h 25m • 1 change
Arrives next day

18h 25m • 1 change
Arrives next day

21h 20m • 1 change

21h 25m • 1 change
Arrives next day

18h 25m • 1 change
Arrives next day

21h 20m • 1 change
Want to know about travelling from Washington to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Washington to St. Louis. However, there are services departing from Washington station and arriving at St. Louis station via Pittsburgh Intermodal Station station. The journey, including transfers, takes approximately 21h 34m.
Washington to St. Louis bus services, operated by Flixbus USA, depart from Washington Union Station.
Washington to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Washington to St. Louis bus tickets online with Flixbus USA and Greyhound USA.
The distance between Washington and St. Louis is 1,140.6 km. The road distance is 1,347 km.
You can take a bus from Washington Union Station to St Louis Bus Station via Pittsburgh Intermodal Station in around 19h 40m.