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Boston to St. Louis buses

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Trip Overview

The average bus between Boston and St. Louis takes 29h 20m and the fastest bus takes 27h 15m. The bus service runs several times per day from Boston to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 20m
Duration
1,263 mi
Distance
$226
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from South Station to Port Authority Bus Terminalbus bus Boston
  2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
28h 35m
$190–407

Boston to St. Louis bus times

Buses run twice daily between Boston and St. Louis. The earliest departure is at 5:30 AM in the morning, and the last departure from Boston is at 8:30 PM which arrives into St. Louis at 11:15 PM. All services require a transfer, and take on average 29h 20m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Boston to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Boston to St. Louis.ExpandLaunch map view
  • Distance: 1,263.2 mi
  • Duration: 29h 20m

What companies run services between Boston, MA, USA and St. Louis, MO, USA?

You can take a bus from South Station to St Louis Bus Station via Port Authority Bus Terminal in around 28h 35m.

Operators